Microangiopathic hemolytic anemia laboratory findings: Difference between revisions
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===Blood Tests=== | ===Blood Tests=== | ||
====Complete Blood Count=== | |||
Laboratory findings consistent with the diagnosis of [[microangiopathic hemolytic anemia]] include<ref name="pmid28447417">{{cite journal| author=Kottke-Marchant K| title=Diagnostic approach to microangiopathic hemolytic disorders. | journal=Int J Lab Hematol | year= 2017 | volume= 39 Suppl 1 | issue= | pages= 69-75 | pmid=28447417 | doi=10.1111/ijlh.12671 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28447417 }} </ref>: | |||
* [[Normochromic normocytic anemia|Normochromic anemia]] | |||
* As red blood cells travel through these damaged vessels, they are shredded. The result is red cell fragmentation and intravascular hemolysis. Under the microscope, damaged red cells have the appearance of schistocytes. | * As red blood cells travel through these damaged vessels, they are shredded. The result is red cell fragmentation and intravascular hemolysis. Under the microscope, damaged red cells have the appearance of schistocytes. | ||
* [[Automated analyser]]s (the machines that perform routine [[full blood count]]s in most hospitals) are generally programmed to flag blood films that display red blood cell fragments or ''schistocytes''. | * [[Automated analyser]]s (the machines that perform routine [[full blood count]]s in most hospitals) are generally programmed to flag blood films that display red blood cell fragments or ''schistocytes''. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 19:19, 21 January 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Findings
Blood Tests
=Complete Blood Count
Laboratory findings consistent with the diagnosis of microangiopathic hemolytic anemia include[1]:
- Normochromic anemia
- As red blood cells travel through these damaged vessels, they are shredded. The result is red cell fragmentation and intravascular hemolysis. Under the microscope, damaged red cells have the appearance of schistocytes.
- Automated analysers (the machines that perform routine full blood counts in most hospitals) are generally programmed to flag blood films that display red blood cell fragments or schistocytes.
References
- ↑ Kottke-Marchant K (2017). "Diagnostic approach to microangiopathic hemolytic disorders". Int J Lab Hematol. 39 Suppl 1: 69–75. doi:10.1111/ijlh.12671. PMID 28447417.