Fever of unknown origin differential diagnosis: Difference between revisions
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#Because of the broad range of differential diagnosis they can be grouped into four categories based on their etiology. | #Because of the broad range of differential diagnosis they can be grouped into four categories based on their etiology. | ||
* Infectious | *Infectious | ||
* Malignant | *Malignant | ||
* Inflammatory | *Inflammatory | ||
* Miscellaneous | *Miscellaneous | ||
==Differential diagnosis== | ==Differential diagnosis== | ||
* | === Infectious === | ||
* | These patients mostly have a history of hospitalization, surgical procedures, contact with infected person or travel to an endemic place. | ||
Examples include: | |||
* Lyme disease | |||
* Histoplasmosis | |||
* Q fever | |||
* Brucellosis | |||
* Toxoplasmosis | |||
* Leptospirosis | |||
* Ehrlichiosis | |||
* Anaplasmosis | |||
* Tuberculosis | |||
* Infectious mononucleosis | |||
* mycobacterium avium infection etc. | |||
=== Malignant === | |||
They are mostly accompanied by loss of weight, decrease in appetite, lymph node enlargement and aquagenic pruritic mostly occurring after hot shower. | |||
Examples include: | |||
* Hodgkin lymphoma | |||
* myeloproliferative disorders | |||
* Colorectal carcinoma | |||
* Hepatoma | |||
* Renal cell carcinoma | |||
* carcinoma of CNS | |||
* Sarcoma etc. | |||
=== Auto Inflammatory === | |||
Mostly they have multi organ involvement and lymphadenopathy along with joint symptoms may be present. | |||
Examples include: | |||
* Systemic lupus erythematosus | |||
* Polymyositis | |||
* Dermatomyositis | |||
* Polymyalgia rheumatica etc. | |||
=== Miscellaneous === | |||
Mostly does not belong to any of the above. | |||
Examples include: | |||
* Familial Mediterranean fever. | |||
* Drug fever | |||
* Thyroiditis | |||
* Hypertriglyceridemia etc. | |||
==References== | ==References== | ||
Revision as of 20:40, 23 January 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: febris continua e causa ignota; febris e causa ignota; febris E.C.I.; FUO; PUO; pyrexia of unknown origin
Overview
- Fever can be the presenting symptom with many diseases, it is therefore important to differentiate fever of unknown origin from all those diseases which present with fever.
- Because of the broad range of differential diagnosis they can be grouped into four categories based on their etiology.
- Infectious
- Malignant
- Inflammatory
- Miscellaneous
Differential diagnosis
Infectious
These patients mostly have a history of hospitalization, surgical procedures, contact with infected person or travel to an endemic place.
Examples include:
- Lyme disease
- Histoplasmosis
- Q fever
- Brucellosis
- Toxoplasmosis
- Leptospirosis
- Ehrlichiosis
- Anaplasmosis
- Tuberculosis
- Infectious mononucleosis
- mycobacterium avium infection etc.
Malignant
They are mostly accompanied by loss of weight, decrease in appetite, lymph node enlargement and aquagenic pruritic mostly occurring after hot shower.
Examples include:
- Hodgkin lymphoma
- myeloproliferative disorders
- Colorectal carcinoma
- Hepatoma
- Renal cell carcinoma
- carcinoma of CNS
- Sarcoma etc.
Auto Inflammatory
Mostly they have multi organ involvement and lymphadenopathy along with joint symptoms may be present.
Examples include:
- Systemic lupus erythematosus
- Polymyositis
- Dermatomyositis
- Polymyalgia rheumatica etc.
Miscellaneous
Mostly does not belong to any of the above.
Examples include:
- Familial Mediterranean fever.
- Drug fever
- Thyroiditis
- Hypertriglyceridemia etc.