Pancreatic fistula differential diagnosis

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Overview

Differential diagnosis of pancreatic fistula may include chronic liver disease, renal failure, heart failure, malignancy, pleural effusion, pancreatitis, retroperitoneal bleeding and bowel ischemia.

Differentiating Pancreatic fistula from other Diseases

Differential diagnosis of a pancreatic fistula may include evaluation for:

1. Chronic liver disease leading to abdominal ascites
2. Renal failure
3. Heart failure
4. Malignancy
5. Conditions leading to pleural effusion such as malignancy, trauma and infections
6. Pancreatitis
7. Retroperitoneal bleeding
8. Bowel ischemia

Diseases	Symptoms	Physical examination	Lab Findings
Chronic liver disease	Jaundice Ascites Pruritus	Spider angiomas Palmar erythema Yellow skin	Prolonged prothrombin time (INR>1.5) Elevated aminotransferase level Elevated bilirubin level low platelet count
Renal failure	Abdominal distention (serositis) Bleeding tendency Unintentional weight loss Decreased mental acquity	Uremic fetor (foul smell) Bruises Pericardial friction rub (uremic pericarditis)	Albuminuria Hematuria Pyuria Metabolic acidosis
Heart failure
Malignancy
Pancreatitis
Retroperitoneal bleeding
Bowel ischemia
pleural effusion