B-cell lymphoma classification: Difference between revisions

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==Overview==
==Overview==
==Classification==
==Classification==
B-cell lymphomas include both [[Hodgkin's lymphoma]]s and most Non-Hodgkins lymphomas. They are typically divided into low and high grade, typically corresponding to indolent (slow-growing) lymphomas and aggressive lymphomas, respectively. . The most commonly used classification system is the WHO classification, a convergence of more than one, older classification systems.  
B-cell lymphomas include both [[Hodgkin's lymphoma]]s and most Non-Hodgkins lymphomas.  
*[[Hodgkin's lymphoma]] may be classified according to the [[World Health Organization|World Health Organisation]] classification system into 2 groups:<ref name="pmid26980727">{{cite journal |vauthors=Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, Advani R, Ghielmini M, Salles GA, Zelenetz AD, Jaffe ES |title=The 2016 revision of the World Health Organization classification of lymphoid neoplasms |journal=Blood |volume=127 |issue=20 |pages=2375–90 |date=May 2016 |pmid=26980727 |pmc=4874220 |doi=10.1182/blood-2016-01-643569 |url=}}</ref>
**Nodular lymphocyte predominant Hodgkin lymphoma
**Classical Hodgkin lymphoma (includes 4 subtypes)
***Nodular sclerosis classical Hodgkin lymphoma
***Lymphocyte-rich classical Hodgkin lymphoma
***Mixed cellularity classical Hodgkin lymphoma
***Lymphocyte-depleted classical Hodgkin lymphoma
*Non-Hodgkin lymphoma may be classified according to the [[World Health Organization|World Health Organisation]] classification system into 2 groups:<ref name="pmid26980727">{{cite journal |vauthors=Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, Advani R, Ghielmini M, Salles GA, Zelenetz AD, Jaffe ES |title=The 2016 revision of the World Health Organization classification of lymphoid neoplasms |journal=Blood |volume=127 |issue=20 |pages=2375–90 |date=May 2016 |pmid=26980727 |pmc=4874220 |doi=10.1182/blood-2016-01-643569 |url=}}</ref><ref name="”cancer">National Cancer Institute. Physician Data Query Database 2015.http://www.cancer.gov/publications/pdq</ref>
**B-cell neoplasms
**T-cell and putative NK-cell neoplasms
*Non-Hodgkin lymphoma may also be classified according to rate of growth<ref name="CCS">{{cite web | title = Canadian Cancer Society Grades of non-Hodgkin lymphoma
| url =http://www.cancer.ca/en/cancer-information/cancer-type/non-hodgkin-lymphoma/grading/?region=ab}}</ref>
**High-grade (aggressive)
**Low-grade (indolent)


===Most common===
===Most common===

Revision as of 17:30, 14 January 2022

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Classification

B-cell lymphomas include both Hodgkin's lymphomas and most Non-Hodgkins lymphomas.

  • Hodgkin's lymphoma may be classified according to the World Health Organisation classification system into 2 groups:[1]
    • Nodular lymphocyte predominant Hodgkin lymphoma
    • Classical Hodgkin lymphoma (includes 4 subtypes)
      • Nodular sclerosis classical Hodgkin lymphoma
      • Lymphocyte-rich classical Hodgkin lymphoma
      • Mixed cellularity classical Hodgkin lymphoma
      • Lymphocyte-depleted classical Hodgkin lymphoma
  • Non-Hodgkin lymphoma may be classified according to the World Health Organisation classification system into 2 groups:[1][2]
    • B-cell neoplasms
    • T-cell and putative NK-cell neoplasms
  • Non-Hodgkin lymphoma may also be classified according to rate of growth[3]
    • High-grade (aggressive)
    • Low-grade (indolent)

Most common

Five account for nearly three out of four patients with non-Hodgkin lymphoma:[4]

Rare

The remaining forms are much less common:[4]

Others

Additionally, some researchers separate out lymphomas that appear result from other immune system disorders, such as AIDS-related lymphoma.

Classic Hodgkin's lymphoma and nodular lymphocyte predominant Hodgkin's lymphoma are now considered forms of B-cell lymphoma.[5]

References

  1. 1.0 1.1 Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, Advani R, Ghielmini M, Salles GA, Zelenetz AD, Jaffe ES (May 2016). "The 2016 revision of the World Health Organization classification of lymphoid neoplasms". Blood. 127 (20): 2375–90. doi:10.1182/blood-2016-01-643569. PMC 4874220. PMID 26980727.
  2. National Cancer Institute. Physician Data Query Database 2015.http://www.cancer.gov/publications/pdq
  3. "Canadian Cancer Society Grades of non-Hodgkin lymphoma".
  4. 4.0 4.1 "The Lymphomas" (PDF). The Leukemia & Lymphoma Society. May 2006. pp. p. 12. Retrieved 2008-04-07.
  5. "HMDS: Hodgkin's Lymphoma". Archived from the original on 4 March 2009. Retrieved 2009-02-01.

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