Allergic conjunctivitis differential diagnosis: Difference between revisions

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! Diseases !! Clinical manifestations !! Para-clinical findings !! Gold standard !! Additional findings
! Diseases !! Clinical manifestations !! Para-clinical findings !! Gold standard !! Additional findings
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| [[Bacterial]] [[conjunctivitis]] ||Bilateral [[matting]] of the [[eyelids]] in the morning, [[Mucopurulent]] [[discharge]], [[conjunctival]] [[hyperemia]], no previous history of [[conjunctivitis]]<ref name="pmid15201195">{{cite journal| author=Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC| title=Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms. | journal=BMJ | year= 2004 | volume= 329 | issue= 7459 | pages= 206-10 | pmid=15201195 | doi=10.1136/bmj.38128.631319.AE | pmc=487734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15201195  }} </ref>  ||-------------||[[Conjunctival]] [[cultures]] || [[Itching]] , [[burning]], [[serous]] or no [[discharge]]<ref name="pmid15201195">{{cite journal| author=Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC| title=Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms. | journal=BMJ | year= 2004 | volume= 329 | issue= 7459 | pages= 206-10 | pmid=15201195 | doi=10.1136/bmj.38128.631319.AE | pmc=487734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15201195  }} </ref>
| [[Bacterial]] [[conjunctivitis]] ||Bilateral [[matting]] of the [[eyelids]] in the morning, [[Mucopurulent]] [[discharge]], [[conjunctival]] [[hyperemia]], no previous history of [[conjunctivitis]]<ref name="pmid15201195">{{cite journal| author=Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC| title=Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms. | journal=BMJ | year= 2004 | volume= 329 | issue= 7459 | pages= 206-10 | pmid=15201195 | doi=10.1136/bmj.38128.631319.AE | pmc=487734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15201195  }} </ref>  ||-------------x-----------||[[Conjunctival]] [[cultures]] || [[Itching]] , [[burning]], [[serous]] or no [[discharge]]<ref name="pmid15201195">{{cite journal| author=Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC| title=Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms. | journal=BMJ | year= 2004 | volume= 329 | issue= 7459 | pages= 206-10 | pmid=15201195 | doi=10.1136/bmj.38128.631319.AE | pmc=487734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15201195  }} </ref>
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| [[Viral]] [[conjunctivitis]] || Thin, watery [[discharge]] with intensely [[hyperemic]] response<ref name="pmid24150468">{{cite journal| author=Azari AA, Barney NP| title=Conjunctivitis: a systematic review of diagnosis and treatment. | journal=JAMA | year= 2013 | volume= 310 | issue= 16 | pages= 1721-9 | pmid=24150468 | doi=10.1001/jama.2013.280318 | pmc=4049531 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24150468  }} </ref>, [[periauricular]] [[lymphadenopathy]]<ref name="pmid18249256">{{cite journal| author=Mahmood AR, Narang AT| title=Diagnosis and management of the acute red eye. | journal=Emerg Med Clin North Am | year= 2008 | volume= 26 | issue= 1 | pages= 35-55, vi | pmid=18249256 | doi=10.1016/j.emc.2007.10.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18249256  }} </ref>  ||-------------- || [[Viral]] [[cell]] [[cultures]], [[PCR]] for [[viral]] [[DNA]] detection<ref name="pmid10845603">{{cite journal| author=Elnifro EM, Cooper RJ, Klapper PE, Yeo AC, Tullo AB| title=Multiplex polymerase chain reaction for diagnosis of viral and chlamydial keratoconjunctivitis. | journal=Invest Ophthalmol Vis Sci | year= 2000 | volume= 41 | issue= 7 | pages= 1818-22 | pmid=10845603 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10845603  }} </ref>  || -
| [[Viral]] [[conjunctivitis]] || Thin, watery [[discharge]] with intensely [[hyperemic]] response<ref name="pmid24150468">{{cite journal| author=Azari AA, Barney NP| title=Conjunctivitis: a systematic review of diagnosis and treatment. | journal=JAMA | year= 2013 | volume= 310 | issue= 16 | pages= 1721-9 | pmid=24150468 | doi=10.1001/jama.2013.280318 | pmc=4049531 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24150468  }} </ref>, [[periauricular]] [[lymphadenopathy]]<ref name="pmid18249256">{{cite journal| author=Mahmood AR, Narang AT| title=Diagnosis and management of the acute red eye. | journal=Emerg Med Clin North Am | year= 2008 | volume= 26 | issue= 1 | pages= 35-55, vi | pmid=18249256 | doi=10.1016/j.emc.2007.10.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18249256  }} </ref>  ||--------------x---------- || [[Viral]] [[cell]] [[cultures]], [[PCR]] for [[viral]] [[DNA]] detection<ref name="pmid10845603">{{cite journal| author=Elnifro EM, Cooper RJ, Klapper PE, Yeo AC, Tullo AB| title=Multiplex polymerase chain reaction for diagnosis of viral and chlamydial keratoconjunctivitis. | journal=Invest Ophthalmol Vis Sci | year= 2000 | volume= 41 | issue= 7 | pages= 1818-22 | pmid=10845603 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10845603  }} </ref>  || ----------x----------
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| [[Autoimmune]] [[eye]] [[disease]] || Dry or red [[eyes]], [[foreign-body]] sensation, [[pruritus]], [[photophobia]]<ref name="pmid12358224">{{cite journal| author=Patel SJ, Lundy DC| title=Ocular manifestations of autoimmune disease. | journal=Am Fam Physician | year= 2002 | volume= 66 | issue= 6 | pages= 991-8 | pmid=12358224 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12358224  }} </ref>  || Abnormal [[Schirmer's]] test, deranged [[visual]] [[acuity]], [[proptosis]], [[exposure keratitis]]<ref name="pmid12358224">{{cite journal| author=Patel SJ, Lundy DC| title=Ocular manifestations of autoimmune disease. | journal=Am Fam Physician | year= 2002 | volume= 66 | issue= 6 | pages= 991-8 | pmid=12358224 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12358224  }} </ref> || [[Autoimmune]] panel of [[blood]] || [[Pain]], [[visual]] changes, complete loss of [[vision]]<ref name="pmid12358224">{{cite journal| author=Patel SJ, Lundy DC| title=Ocular manifestations of autoimmune disease. | journal=Am Fam Physician | year= 2002 | volume= 66 | issue= 6 | pages= 991-8 | pmid=12358224 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12358224  }} </ref>
| [[Autoimmune]] [[eye]] [[disease]] || Dry or red [[eyes]], [[foreign-body]] sensation, [[pruritus]], [[photophobia]]<ref name="pmid12358224">{{cite journal| author=Patel SJ, Lundy DC| title=Ocular manifestations of autoimmune disease. | journal=Am Fam Physician | year= 2002 | volume= 66 | issue= 6 | pages= 991-8 | pmid=12358224 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12358224  }} </ref>  || Abnormal [[Schirmer's]] test, deranged [[visual]] [[acuity]], [[proptosis]], [[exposure keratitis]]<ref name="pmid12358224">{{cite journal| author=Patel SJ, Lundy DC| title=Ocular manifestations of autoimmune disease. | journal=Am Fam Physician | year= 2002 | volume= 66 | issue= 6 | pages= 991-8 | pmid=12358224 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12358224  }} </ref> || [[Autoimmune]] panel of [[blood]] || [[Pain]], [[visual]] changes, complete loss of [[vision]]<ref name="pmid12358224">{{cite journal| author=Patel SJ, Lundy DC| title=Ocular manifestations of autoimmune disease. | journal=Am Fam Physician | year= 2002 | volume= 66 | issue= 6 | pages= 991-8 | pmid=12358224 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12358224  }} </ref>
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| [[Acne]] [[rosacea]] ||Minor irritation, gritty sensation, dryness, blurry vision, [[blepharitis]] and [[conjunctivitis]] ||------------ ||------------- ||[[Lid]] margin and [[conjunctival]] [[telangiectasias]], [[eyelid]] thickening, [[eyelid]] crusts and scales, [[chalazion]], [[hordeolum]], punctate [[epithelial]] erosions, [[corneal]] infiltrates, [[corneal]] [[ulcers]], [[corneal]] scars, and [[vascularization]]
| [[Acne]] [[rosacea]] ||Minor irritation, gritty sensation, dryness, blurry vision, [[blepharitis]] and [[conjunctivitis]] ||------------x----------- ||-------------x----------- ||[[Lid]] margin and [[conjunctival]] [[telangiectasias]], [[eyelid]] thickening, [[eyelid]] crusts and scales, [[chalazion]], [[hordeolum]], punctate [[epithelial]] erosions, [[corneal]] infiltrates, [[corneal]] [[ulcers]], [[corneal]] scars, and [[vascularization]]
|-}
|-}


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}

Revision as of 18:07, 22 August 2022

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  1. ↑ 1.0 1.1 Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC (2004). "Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms". BMJ. 329 (7459): 206–10. doi:10.1136/bmj.38128.631319.AE. PMC 487734. PMID 15201195.
  2. ↑ Azari AA, Barney NP (2013). "Conjunctivitis: a systematic review of diagnosis and treatment". JAMA. 310 (16): 1721–9. doi:10.1001/jama.2013.280318. PMC 4049531. PMID 24150468.
  3. ↑ Mahmood AR, Narang AT (2008). "Diagnosis and management of the acute red eye". Emerg Med Clin North Am. 26 (1): 35–55, vi. doi:10.1016/j.emc.2007.10.002. PMID 18249256.
  4. ↑ Elnifro EM, Cooper RJ, Klapper PE, Yeo AC, Tullo AB (2000). "Multiplex polymerase chain reaction for diagnosis of viral and chlamydial keratoconjunctivitis". Invest Ophthalmol Vis Sci. 41 (7): 1818–22. PMID 10845603.
  5. ↑ 5.0 5.1 5.2 Patel SJ, Lundy DC (2002). "Ocular manifestations of autoimmune disease". Am Fam Physician. 66 (6): 991–8. PMID 12358224.
Differential diagnosis of allergic conjunctivitis
Diseases Clinical manifestations Para-clinical findings Gold standard Additional findings
Bacterial conjunctivitis Bilateral matting of the eyelids in the morning, Mucopurulent discharge, conjunctival hyperemia, no previous history of conjunctivitis[1] -------------x----------- Conjunctival cultures Itching , burning, serous or no discharge[1]
Viral conjunctivitis Thin, watery discharge with intensely hyperemic response[2], periauricular lymphadenopathy[3] --------------x---------- Viral cell cultures, PCR for viral DNA detection[4] ----------x----------
Autoimmune eye disease Dry or red eyes, foreign-body sensation, pruritus, photophobia[5] Abnormal Schirmer's test, deranged visual acuity, proptosis, exposure keratitis[5] Autoimmune panel of blood Pain, visual changes, complete loss of vision[5]
Acne rosacea Minor irritation, gritty sensation, dryness, blurry vision, blepharitis and conjunctivitis ------------x----------- -------------x----------- Lid margin and conjunctival telangiectasias, eyelid thickening, eyelid crusts and scales, chalazion, hordeolum, punctate epithelial erosions, corneal infiltrates, corneal ulcers, corneal scars, and vascularization
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