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The symptoms are due to release of [[histamine]] and other active substances by [[mast cell]]s, which stimulate dilation of blood vessels, irritate nerve endings and increase secretion of tears.
The symptoms are due to release of [[histamine]] and other active substances by [[mast cell]]s, which stimulate dilation of blood vessels, irritate nerve endings and increase secretion of tears.
==History and Symptoms==
==History and Symptoms==
The [[conjunctiva]] is a thin membrane that covers the eye.  When an allergen irritates the conjunctiva, common symptoms that occur in the eye include: ocular itching, eyelid swelling, tearing, photophobia, watery discharge, and foreign body sensation (with pain).<ref name="Cunningham">{{cite journal | author = Whitcup SM | title = Recent advances in ocular therapeutics | journal = Int Ophthalmol Clin | editor = Cunningham  ET Jr, Ng EWM | volume = 46 | issue = 4 | pages = 1–6 | year = 2006 | pmid = 17060786 | doi = 10.1097/01.iio.0000212140.70051.33 }}</ref>
===[[Clinical]] [[History]]===
 
===[[Symptoms]]===
Itching is the most typical symptom of ocular allergy and more than 75% of patients report this symptom when seeking treatment.<ref name= "Cunningham"/>
 
Symptoms are usually worse for patients when the weather is warm and dry, whereas cooler temperatures and rain tend to assuage symptoms.
 
A study by Klein et al. showed that in addition to the physical discomfort allergic conjunctivitis causes, it also alters patients' routines, with patients limiting certain activities such as going outdoors, reading, sleeping, and driving.<ref name= "Cunningham"/> Therefore, treating patients with allergic conjunctivitis may improve their everyday "[[quality of life]]."


==References==
==References==

Revision as of 18:01, 28 August 2022

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The symptoms are due to release of histamine and other active substances by mast cells, which stimulate dilation of blood vessels, irritate nerve endings and increase secretion of tears.

History and Symptoms

Clinical History

Symptoms

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