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'''For patient information, click [[Liposarcoma (patient information)|here]]'''
{{DiseaseDisorder infobox |
{{DiseaseDisorder infobox |
   Name        = Liposarcoma |
   Name        = Liposarcoma |
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   ICDO        = {{ICDO|8850|3}} |
   ICDO        = {{ICDO|8850|3}} |
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{{SI}}
{{Liposarcoma}}
{{CMG}}
{{CMG}}


{{Editor Help}}
==[[Liposarcoma overview|Overview]]==


==Overview==
==[[Liposarcoma classification|Classification]]==


'''Liposarcoma''' is a [[malignant]] [[tumor]] that arises in [[Adipose tissue|fat cells]] in deep soft tissue, such as that inside the thigh or in the [[retroperitoneum]].
==[[Liposarcoma historical perspective|Historical Perspective]]==


They are typically large bulky tumors which tend to have multiple smaller satellites extending beyond the main confines of the tumor.
==[[Liposarcoma pathophysiology|Pathophysiology]]==


Because of their rarity, liposarcomas are best treated by a sarcoma center. 
==[[Liposarcoma epidemiology and demographics|Epidemiology & Demographics]]==


==Symptoms==
==[[Liposarcoma epidemiology and demographics|Risk Factors]]==
Patients usually note a deep seated mass in their soft tissue. Only when the tumor is very large do symptoms of pain or functional disturbances occur.


Retroperitoneal tumors may present with signs of [[weight loss]] and [[emaciation]] and [[abdominal pain]]. These tumors may also compress the kidney or ureter leading to [[kidney failure]].
==[[Liposarcoma screening|Screening]]==


==Incidence/Prevalence==
==[[Liposarcoma causes|Causes]]==
Most frequent in middle-aged and older adults (age 40 and above), liposarcomas are the most common of all soft-tissue [[sarcoma]]s. Annually 2.5 cases occur per million population.


==Metastatic Disease==
==[[Liposarcoma differential diagnosis|Differentiating Liposarcoma from other Diseases]]==
The most common sites of metastases from liposarcoma are to the lungs, liver, peritoneal surfaces, and brain (1).


==Prognosis==
==[[Liposarcoma natural history|Natural History, Complications & Prognosis]]==
The prognosis varies depending on the site of origin, the type of cancer cell, the tumor size, the depth, and proximity to lymph nodes. Metastases are common.  The 5 year survival rate for a high-grade liposarcoma is less than 50%. <!-- 2.5 cases per million is international, same site.  -->


==Examples==
==Diagnosis==
[[Liposarcoma history and symptoms|History & Symptoms]] | [[Liposarcoma physical examination|Physical Examination]] | [[Liposarcoma staging|Staging]] | [[Liposarcoma laboratory tests|Lab Tests]] | [[Liposarcoma electrocardiogram|Electrocardiogram]] | [[Liposarcoma chest x ray|Chest X Ray]] | [[Liposarcoma CT|CT]] | [[Liposarcoma MRI|MRI]] | [[Liposarcoma echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Liposarcoma other imaging findings|Other Imaging Findings]] | [[Liposarcoma other diagnostic studies|Other Diagnostic Studies]]


<div align="center">
==Treatment==
<gallery heights="175" widths="175">
[[Liposarcoma medical therapy|Medical Therapy]] | [[Liposarcoma surgery|Surgery]] | [[Liposarcoma primary prevention|Primary Prevention]] | [[Liposarcoma secondary prevention|Secondary Prevention]]
Image:Myxoid-liposarcoma -001.jpg|Myxoid Liposarcoma
</gallery>
</div>


==See also==
==Related chapters==
* [[Lipoma]]
* [[Lipoma]]


==References==
==Resources==
1. Hajdu SI. Pathology of Soft Tissue Tumors, Lea & Febiger, Philadelphia, 1979; pp 250–295.
 
==External links==
* {{eMedicine|derm|856|Liposarcoma}}
*[http://www.thedoctorsdoctor.com/diseases/liposarcoma.htm doctors doctor page]
*[http://www.thedoctorsdoctor.com/diseases/liposarcoma.htm doctors doctor page]
* {{DiseasesDB|31482}}
* {{DiseasesDB|31482}}
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{{Soft tissue tumors and sarcomas}}
{{Soft tissue tumors and sarcomas}}
{{SIB}}
 
[[Category:Disease]]
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Oncology]]
[[Category:Oncology]]
 
[[Category:Surgery]]
 


[[it:Liposarcoma]]
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Revision as of 14:27, 22 January 2012

For patient information, click here

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Liposarcoma Microchapters

Home

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Liposarcoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

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Cost-Effectiveness of Therapy

Future or Investigational Therapies

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Case #1

Liposarcoma On the Web

Most recent articles

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American Roentgen Ray Society Images of Liposarcoma

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X-rays
Echo & Ultrasound
CT Images
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Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Liposarcoma

CDC on Liposarcoma

Liposarcoma in the news

Blogs on Liposarcoma

Directions to Hospitals Treating Liposarcoma

Risk calculators and risk factors for Liposarcoma

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Classification

Historical Perspective

Pathophysiology

Epidemiology & Demographics

Risk Factors

Screening

Causes

Differentiating Liposarcoma from other Diseases

Natural History, Complications & Prognosis

Diagnosis

History & Symptoms | Physical Examination | Staging | Lab Tests | Electrocardiogram | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention

Related chapters

Resources

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