GNA13

Guanine nucleotide binding protein (G protein), alpha 13
Identifiers
Symbols	GNA13 ; G13; MGC46138
External IDs	Template:OMIM5 Template:MGI HomoloGene: 55976
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

WikiDoc Resources for GNA13
Articles
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Evidence Based Medicine
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Commentary
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Definitions
Definitions of GNA13
Patient Resources / Community
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Experimental / Informatics
List of terms related to GNA13

Guanine nucleotide binding protein (G protein), alpha 13, also known as GNA13, is a human gene.

See also

• G protein

Further reading

• Ruppel KM, Willison D, Kataoka H, Wang A, Zheng YW, Cornelissen I, Liya Yin, Xu SM, and Coughlin SR (2005). "Essential role for Galpha 13 in endothelial cells during embryonic development". Proc. Natl. Acad. Sci. U.S.A. 102 (22): 8281–8286. doi:10.1073/pnas.0503326102. PMID 15919816.CS1 maint: Multiple names: authors list (link)
• Downes GB, Gautam N (2000). "The G protein subunit gene families". Genomics. 62 (3): 544–52. doi:10.1006/geno.1999.5992. PMID 10644457.
• Kabouridis PS, Waters ST, Escobar S; et al. (1995). "Expression of GTP-binding protein alpha subunits in human thymocytes". Mol. Cell. Biochem. 144 (1): 45–51. PMID 7791744.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Offermanns S, Laugwitz KL, Spicher K, Schultz G (1994). "G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets". Proc. Natl. Acad. Sci. U.S.A. 91 (2): 504–8. PMID 8290554.CS1 maint: Multiple names: authors list (link)
• Laugwitz KL, Allgeier A, Offermanns S; et al. (1996). "The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families". Proc. Natl. Acad. Sci. U.S.A. 93 (1): 116–20. PMID 8552586.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Offermanns S, Hu YH, Simon MI (1996). "Galpha12 and galpha13 are phosphorylated during platelet activation". J. Biol. Chem. 271 (42): 26044–8. PMID 8824244.CS1 maint: Multiple names: authors list (link)
• Offermanns S, Mancino V, Revel JP, Simon MI (1997). "Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency". Science. 275 (5299): 533–6. PMID 8999798.CS1 maint: Multiple names: authors list (link)
• Macrez-Leprêtre N, Kalkbrenner F, Morel JL; et al. (1997). "G protein heterotrimer Galpha13beta1gamma3 couples the angiotensin AT1A receptor to increases in cytoplasmic Ca2+ in rat portal vein myocytes". J. Biol. Chem. 272 (15): 10095–102. PMID 9092554.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hart MJ, Jiang X, Kozasa T; et al. (1998). "Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13". Science. 280 (5372): 2112–4. PMID 9641916.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fukuhara S, Murga C, Zohar M; et al. (1999). "A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho". J. Biol. Chem. 274 (9): 5868–79. PMID 10026210.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Becker KP, Garnovskaya M, Gettys T, Halushka PV (1999). "Coupling of thromboxane A2 receptor isoforms to Galpha13: effects on ligand binding and signalling". Biochim. Biophys. Acta. 1450 (3): 288–96. PMID 10395940.CS1 maint: Multiple names: authors list (link)
• Windh RT, Lee MJ, Hla T; et al. (1999). "Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins". J. Biol. Chem. 274 (39): 27351–8. PMID 10488065.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brydon L, Roka F, Petit L; et al. (2000). "Dual signaling of human Mel1a melatonin receptors via G(i2), G(i3), and G(q/11) proteins". Mol. Endocrinol. 13 (12): 2025–38. PMID 10598579.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bhattacharyya R, Wedegaertner PB (2000). "Galpha 13 requires palmitoylation for plasma membrane localization, Rho-dependent signaling, and promotion of p115-RhoGEF membrane binding". J. Biol. Chem. 275 (20): 14992–9. doi:10.1074/jbc.M000415200. PMID 10747909.
• Vaiskunaite R, Adarichev V, Furthmayr H; et al. (2000). "Conformational activation of radixin by G13 protein alpha subunit". J. Biol. Chem. 275 (34): 26206–12. doi:10.1074/jbc.M001863200. PMID 10816569.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shi CS, Sinnarajah S, Cho H; et al. (2000). "G13alpha-mediated PYK2 activation. PYK2 is a mediator of G13alpha -induced serum response element-dependent transcription". J. Biol. Chem. 275 (32): 24470–6. doi:10.1074/jbc.M908449199. PMID 10821841.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ponimaskin E, Behn H, Adarichev V; et al. (2000). "Acylation of Galpha(13) is important for its interaction with thrombin receptor, transforming activity and actin stress fiber formation". FEBS Lett. 478 (1–2): 173–7. PMID 10922491.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jin S, Exton JH (2000). "Activation of RhoA by association of Galpha(13) with Dbl". Biochem. Biophys. Res. Commun. 277 (3): 718–21. doi:10.1006/bbrc.2000.3744. PMID 11062019.
• Fukuhara S, Chikumi H, Gutkind JS (2000). "Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho". FEBS Lett. 485 (2–3): 183–8. PMID 11094164.CS1 maint: Multiple names: authors list (link)
• Meigs TE, Fields TA, McKee DD, Casey PJ (2001). "Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release". Proc. Natl. Acad. Sci. U.S.A. 98 (2): 519–24. doi:10.1073/pnas.021350998. PMID 11136230.CS1 maint: Multiple names: authors list (link)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.