Aplastic anemia medical therapy: Difference between revisions
(/* Specific Treatment of Aplastic Anaemia: Immunosuppressive Therapy: ATG and Ciclosporin {{cite journal| author=Marsh JC, Ball SE, Cavenagh J, Darbyshire P, Dokal I, Gordon-Smith EC et al.| title=Guidelines for the diagnosis and management of apl...) |
(/* Specific Treatment of Aplastic Anaemia: Immunosuppressive Therapy: ATG and Ciclosporin {{cite journal| author=Marsh JC, Ball SE, Cavenagh J, Darbyshire P, Dokal I, Gordon-Smith EC et al.| title=Guidelines for the diagnosis and management of apl...) |
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===Immunosuppressive Therapy: ATG and Ciclosporin=== | ===Immunosuppressive Therapy: ATG and Ciclosporin=== | ||
* Immunosuppressive therapy is recommended for: | * [[Immunosuppressive therapy]] is recommended for: | ||
** patients with non-severe [[aplastic anaemia]] who are transfusion dependent | ** patients with non-severe [[aplastic anaemia]] who are transfusion dependent | ||
** patients with severe or very severe disease who are >40 years old, and | ** patients with severe or very severe disease who are >40 years old, and |
Revision as of 15:32, 23 September 2012
Aplastic anemia Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Aplastic anemia medical therapy On the Web |
American Roentgen Ray Society Images of Aplastic anemia medical therapy |
Risk calculators and risk factors for Aplastic anemia medical therapy |
Editor-In-Chief: Aric Hall, M.D., Beth Israel Deaconess Medical Center, Boston, MA [1]
Overview
Medical therapy of aplastic anemia often includes a short course of anti-thymocyte globulin (ATG or anti-lymphocyte globulin) and several months of treatment with cyclosporin to modulate the immune system. Mild chemotherapy with agents such as cyclophosphamide and vincristine may also be effective. Antibodies therapy, such as ATG, targets T-cells, which are believed to attack the bone marrow. Steroids are generally ineffective.
Medical Therapy
Supportive Care in treatment of aplastic anemia [1] (DONOT EDIT)
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Supportive Care
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Specific Treatment of Aplastic Anaemia: General Comments [1] (DONOT EDIT)
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General Comments
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Specific Treatment of Aplastic Anaemia: Human Leucocyte Antigen (HLA)-identical Sibling Donor Transplantation [1] (DONOT EDIT)
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Human Leucocyte Antigen (HLA)-identical Sibling Donor Transplantation
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Specific Treatment of Aplastic Anaemia: Immunosuppressive Therapy: ATG and Ciclosporin [1] (DONOT EDIT)
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Immunosuppressive Therapy: ATG and Ciclosporin
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References
- ↑ 1.0 1.1 1.2 1.3 Marsh JC, Ball SE, Cavenagh J, Darbyshire P, Dokal I, Gordon-Smith EC; et al. (2009). "Guidelines for the diagnosis and management of aplastic anaemia". Br J Haematol. 147 (1): 43–70. doi:10.1111/j.1365-2141.2009.07842.x. PMID 19673883.