Aplastic anemia causes: Difference between revisions
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==Causes== | ==Causes== | ||
===Acquired Causes=== | |||
Many diseases, conditions, and factors can cause aplastic anemia, including: | |||
•Toxins, such as pesticides, arsenic, and benzene. | |||
•Radiation and chemotherapy (treatments for cancer). | |||
•Medicines, such as chloramphenicol (an antibiotic rarely used in the United States). | |||
•Infectious diseases, such as hepatitis, Epstein-Barr virus, cytomegalovirus (si-to-MEG-ah-lo-VI-rus), parvovirus B19, and HIV. | |||
•Autoimmune disorders, such as lupus and rheumatoid arthritis. | |||
•Pregnancy. (Aplastic anemia that occurs during pregnancy often goes away after delivery.) | |||
Sometimes, cancer from another part of the body can spread to the bone and cause aplastic anemia. | |||
===Inherited Causes=== | |||
Certain inherited conditions can damage the stem cells and lead to aplastic anemia. Examples include Fanconi anemia, Shwachman-Diamond syndrome, dyskeratosis (DIS-ker-ah-TO-sis) congenita, and Diamond-Blackfan anemia. | |||
* [[Idiopathic]] | * [[Idiopathic]] | ||
* [[Autoimmune disorder]] | * [[Autoimmune disorder]] | ||
Revision as of 13:31, 24 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The cause of the damage can be acquired or inherited. Acquired aplastic anemia is more common, and sometimes it's only temporary. Inherited aplastic anemia is rare. More than half of the cases of aplastic anemia are idiopathic. Chemicals, drugs, viral infections, collagen vascular diseases, and thymoma can be implicated as the causative factor in the other cases. Some research suggests that stem cell damage may occur because the body's immune system attacks its own cells by mistake.
Causes
Acquired Causes
Many diseases, conditions, and factors can cause aplastic anemia, including: •Toxins, such as pesticides, arsenic, and benzene. •Radiation and chemotherapy (treatments for cancer). •Medicines, such as chloramphenicol (an antibiotic rarely used in the United States). •Infectious diseases, such as hepatitis, Epstein-Barr virus, cytomegalovirus (si-to-MEG-ah-lo-VI-rus), parvovirus B19, and HIV. •Autoimmune disorders, such as lupus and rheumatoid arthritis. •Pregnancy. (Aplastic anemia that occurs during pregnancy often goes away after delivery.) Sometimes, cancer from another part of the body can spread to the bone and cause aplastic anemia.
Inherited Causes
Certain inherited conditions can damage the stem cells and lead to aplastic anemia. Examples include Fanconi anemia, Shwachman-Diamond syndrome, dyskeratosis (DIS-ker-ah-TO-sis) congenita, and Diamond-Blackfan anemia.
- Idiopathic
- Autoimmune disorder
- Viral hepatitis
- Collagen vascular disease
- Thymoma
- Exposure to substances such as