POEMS syndrome diagnostic criteria: Difference between revisions
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{{POEMS syndrome}} | {{POEMS syndrome}} | ||
{{CMG}} | {{CMG}} | ||
==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Needs overview]] | |||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
[[Category:Neurological disorders]] | [[Category:Neurological disorders]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
[[Category:Syndromes]] | [[Category:Syndromes]] | ||
[[Category: | [[Category:Disease]] | ||
[[es:Síndrome POEMS]] | [[es:Síndrome POEMS]] | ||
Revision as of 14:40, 2 January 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Diagnostic Criteria
The most recent criteria for the diagnosis of POEMS syndrome require that all of the following be present:
- Polyneuropathy
- A monoclonal plasma-cell proliferative disorder
- One or more of the following major criteria:
- Sclerotic bone lesions
- Castleman's disease
- Elevated VEGF levels
- One or more of the following minor criteria:
- Organomegaly (enlarged spleen, liver or lymph nodes)
- Extravascular volume overload (oedema, pleural effusion or ascites)
- Endocrinopathy (adrenal, pituitary, gonadal, parathyroid); diabetes or hypothyroidism alone are insufficient
- Skin changes
- Papilloedema
- Thrombocytosis or polycythaemia
In addition, clubbing, weight loss, and hyperhidrosis can also be seen.