Hypertensive nephropathy risk factors: Difference between revisions
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==Risk Factors== | ==Risk Factors== | ||
* High [[systolic blood pressure]] is a very strong risk factor for development of hypertensive nephrosclerosis. | * High [[systolic blood pressure]] is a very strong risk factor for the development of hypertensive nephrosclerosis. | ||
* APOL1 gene | * APOL1 gene | ||
** This gene has been identified to accelerate the progression of renal disease in African- American hypertensive patients. | ** This gene has been identified to accelerate the progression of renal disease in African- American hypertensive patients. |
Revision as of 19:49, 12 March 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]
Risk Factors
- High systolic blood pressure is a very strong risk factor for the development of hypertensive nephrosclerosis.
- APOL1 gene
- This gene has been identified to accelerate the progression of renal disease in African- American hypertensive patients.
- The Framingham heart study showed that a combination of hypertension with mild reduction in glomerular filtration rate was a risk factor for development of chronic renal insufficiency.
- Diabetes, smoking, obesity and high levels of low density lipoproteins also contribute to the progression of renal damage secondary to hypertension.