Liposarcoma CT
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Liposarcoma CT On the Web |
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American Roentgen Ray Society Images of Liposarcoma CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
CT imaging is one of the most important tests for the diagnosis of liposarcoma. CT should assess the size, location and depth of the liposarcoma, as well as the lymph node involvement and distant metastasis. CT findings can be correlated with the histopathological subtype.
CT Scan
- Imaging findings of liposarcoma are frequently characteristic and correlate with each specific subtype.[1]
- Focal or diffuse areas of fat associated with nonlipomatous components are commonly detected on computed tomographic or magnetic resonance images.
- The appearance and morphologic relationship between these areas frequently allow identification of the specific histologic subtype of liposarcoma.
- CT scan is also used to determine the stage of the disease assessing the presence of lymph nodes and distant metastasis.[2]
CT Findings According to the Liposarcoma Subtype
| Subtypes | Density | Margins | Fat Content | Nodular muscle-density area in tumor | Calcifications | Necrotic or cystic areas |
| Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) | Fat | Smooth regular | > 65% | ++ | Few/none | + |
| Dedifferentiated liposarcoma (DDL) | Mixed | Rough irregular | 30-60% | +++ | Few/none | ++ |
| Myxoid/round cell liposarcoma (ML/RCL) | Mixed | Rough irregular | 25-50% | + | Common | +++ |
| Pleomorphic liposarcoma (PL) | Soft tissue | Incomplete irregular | 6-25% | + | Few/none | + |
| Mixed-type liposarcoma | Mixed | Smooth regular | 30-60% | ++ | Common | + |
| Table adapted from CT Manifestations in Histologic Subtypes of Retroperitoneal Liposarcoma[3] | ||||||
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References
- ↑ Kim, T; Murakami, T; Oi, H; Tsuda, K; Matsushita, M; Tomoda, K; Fukuda, H; Nakamura, H (1996). "CT and MR imaging of abdominal liposarcoma". American Journal of Roentgenology. 166 (4): 829–833. doi:10.2214/ajr.166.4.8610559. ISSN 0361-803X.
- ↑ Kumarasamy, Narmadan A.; Gayer, Gabriela (2011). "Retroperitoneal Sarcomas". Seminars in Ultrasound, CT and MRI. 32 (5): 422–432. doi:10.1053/j.sult.2011.06.002. ISSN 0887-2171.
- ↑ Jing Lu, Qin Qin, Liang-Liang Zhan, Xi Yang, Qing Xu, Jing Yu, Li-Na Dou, Hao Zhang, Yan Yang, Xiao-Chen Chen, Yue-Hua Yang, Hong-Yan Cheng & Xin-Chen Sun (2014). "Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma". Asian Pacific journal of cancer prevention : APJCP. 15 (15): 6041–6046. PMID 25124571.