Uveitis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]

Laboratory findings

There are no diagnostic lab findings associated with uveitis. The presence of certain non-specific laboratory findings, in the presence of uveitis, may be suggestive of certain underlying causes such as:

White blood cells

• Elevated white blood cells with a left shift may be suggestive of an underlying infection.
• Decreased white blood cell count may be indicative of an immunosuppressed state.

ESR and CRP

• Elevated ESR and CRP may be suggestive of an underlying infection or inflammatory condition.

CBC and differentials

• A low hematocrit with microcytosis or marginal normocytosis may be indicative of blood loss by inflammatory bowel disease, or any chronic inflammatory disorder.

Iron studies

• Low ferritin with a high TIBC is suggestive of chronic blood loss by inflammatory bowel disease.
• High ferritin may be suggestive of anemia of chronic inflammatory conditions.

HLA subtyping

• HLA-B27
• HLA-A29
• HLA-B9
• HLA-B15

All associated with different underlying conditions of uveitis.

References

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