Endocarditis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maliha Shakil, M.D. [2]
Overview
Risk factors for endocarditis include prosthetic heart valves, valvular heart disease, congenital heart disease, intravenous drug use, age-related degenerative valvular lesions, immunosuppression, and colon cancer.[1]
Risk Factors
Common risk factors in the development of infective endocarditis are:[1]
- Prosthetic heart valves
- Valvular heart disease (mitral valve prolapse is the most common valvular lesion that predisposes to endocarditis)[2]
- Intravenous drug abuse
- Intracardiac devices, such as implantable cardioverter-defibrillators
- Age-related degenerative valvular lesions
- Hemodialysis
- Congenital heart disease
- History of rheumatic heart disease
- Diabetes mellitus
- HIV/AIDS
- Immunosuppression
- Colon cancer
Common risk factors in the development of non-bacterial thrombotic endocarditis are:[3]
- Hypercoagulable state such as pregnancy and systemic bacterial infection
- Malignancy especially mucin-producing adenocarcinomas (most commonly associated with pancreatic adenocarcinomas)
- Systemic lupus erythematosus
- trauma (e.g., catheters)
References
- ↑ 1.0 1.1 Infective endocarditis. Wikipedia (2015). URL=https://en.wikipedia.org/wiki/Infective_endocarditis#Pathogenesis Accessed on September 22, 2015
- ↑ Mylonakis E, Calderwood SB (2001). "Infective endocarditis in adults". N Engl J Med. 345 (18): 1318–30. doi:10.1056/NEJMra010082. PMID 11794152.
- ↑ Non-bacterial thrombotic endocarditis. Wikipedia (2015). URL=https://en.wikipedia.org/wiki/Nonbacterial_thrombotic_endocarditis Accessed on September 23, 2015