Familial adenomatous polyposis medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2], Mohamad Alkateb, MBBCh [3]
Overview
The mainstay of treatment for familial adenomatous polyposis is surgery. However, non-steroidal anti-inflammatory drugs (NSAIDs) is recommended to decrease the size and number of colon polyps.
Medical Therapy
- The mainstay of treatment for familial adenomatous polyposis is surgery.
- Pharmacologic medical therapies for familial adenomatous polyposis include non-steroidal anti-inflammatory drugs (NSAIDs), [therapy 2], and/or [therapy 3].[1]
- Preferred regimen (1): Sulindac
- Preferred regimen (2): Celecoxib 400 mg twice daily for 6 months
Note (1): non-steroidal anti-inflammatory drugs (NSAIDs) decrease the size and number of colon polyps.
References
- ↑ King JE, Dozois RR, Lindor NM, Ahlquist DA (2000). "Care of patients and their families with familial adenomatous polyposis". Mayo Clin. Proc. 75 (1): 57–67. doi:10.4065/75.1.57. PMID 10630758.