Cryptogenic organizing pneumonia medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
Medical Therapy
- The mainstay of the therapy is pharmacotherapy.
- Corticosteroids are used as first-line treatment for patients with the symptomatic and progressive disease.
- For asymptomatic mass lesions or nonprogressive disease, treatment is not required, observation is required till they become symptomatic.
Regimens of corticosteroids for symptomatic and progressive disease are:
- Preferred regimen (1): Methylprednisolone 1 mg/kg (60 mg/d) PO q24h for 1 to 3 months.
- Followed by (2): Methylprednisolone 10 to 20 mg/d PO q24h or or every other day for a 1 year.