Monoclonal gammopathy of undetermined significance MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2]

Overview

There are no specific MRI scan findings associated with MGUS. However, MRI may be helpful in the diagnosis of complications and differentiate between various patterns of multiple myeloma, which include normal focal lesions, variegated/salt-and-pepper pattern and diffuse disease in the absence of bone destruction.

MRI

There are no specific MRI scan findings associated with MGUS. However, MRI may be helpful in the diagnosis of complications and differentiate between various patterns of multiple myeloma, which include:[1][2]

  • Normal focal lesions
  • Variegated/salt-and-pepper pattern
  • Diffuse disease in the absence of bone destruction

References

  1. Baur A, Stäbler A, Bartl R, Lamerz R, Reiser M (June 1996). "[Infiltration patterns of plasmacytomas in magnetic resonance tomography]". Rofo (in German). 164 (6): 457–63. doi:10.1055/s-2007-1015689. PMID 8688501.
  2. Mena E, Choyke P, Tan E, Landgren O, Kurdziel K (January 2011). "Molecular imaging in myeloma precursor disease". Semin. Hematol. 48 (1): 22–31. doi:10.1053/j.seminhematol.2010.11.006. PMC 3023940. PMID 21232655.

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