Fanconi anemia risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shyam Patel [2]

Risk factors

There are no particular risk factors for Fanconi anemia. This is a genetic disorder that is caused by a mutation in genes involved in DNA damage response. Patients with Fanconi anemia are more susceptible to malignancy such as acute myeloid leukemia, and a risk factor for development of malignancies includes exposure to radiation and carcinogens.