Haff disease laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S

Overview

Laboratory findings

Since Haff disease causes rhabdomyolysis, the approach to the evaluation of rhabdomyolysis should be as follows:

  • CBC (complete blood count)
  • Creatine kinase (three-five times the upper limit of normal values of 100 to 400 IU/L)[1]
  • Chemistries (hyperkalemia, hyperphosphatemia, and hypocalcemia)
  • Liver function test
  • Urine pH
  • Urinalysis
    • Blood (+)
    • No red blood cells on microscopy (seen in either hemoglobinuria or myoglobinuria)

References

  1. "StatPearls". 2022. PMID 28846335.

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