B-cell lymphoma physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Adnan Ezici, M.D [2]

Overview

The following physical examination findings may be present among patients with Hodgkin's lymphoma: fever, pruritus, petechiae, jaundice, peripheral lymphadenopathy, central lymphadenopathy, wheezing , chest tenderness, abdominal tenderness, hepatomegaly, splenomegaly and peripheral lymphadenopathy.

Physical Examination

The following physical examination findings may be present among patients with B cell lymphomas:^[1]^[2]^[3]^[4]^[5]

Appearance of the Patient

Appearance of the Patients with B cell lymphomas depends on the stage of disease. Patients may present with cachexia in late disease stage.

Vital Signs

Fever
Tachypnea
Asymmetric pulse

Skin

Skin examination of patients with B cell lymphomas include:
- Pallor
- Pruritus
- Petechiae
- Jaundice

HEENT

Abnormalities of the head/hair may include:
- Icteric sclera
- Nystagmus
Patients may develop superior vena cava syndrome, which may present with:
- Swelling of the face
- Facial flushing/redness face or cheeks
- Facial tenderness
- Drooping eyelid
- Swelling around the eye

Neck

Cervical lymphadenopathy

Lungs

Thoracic masses suggestive of central lymphadenopathy
Chest tenderness
Pleural effusion may develop, which has signs and symptoms such as:
- Wheezing
- Decreased breath sounds
- Asymmetric chest expansion
- Hyperresonance lungs on chest auscultation

Heart

Cardiovascular examination of patients with B cell lymphomas is usually normal.

Abdomen

Abdominal examination of patients with B cell lymphomas include:
- Abdominal distension
- Abdominal tenderness
- Hepatosplenomegaly
- Abdominal masses suggestive of central lymphadenopathy

Back

Back examination of patients with B cell lymphomas is usually normal.

Genitourinary

Genitourinary examination of patients with B cell lymphomas is usually normal.

Neuromuscular

Neuromuscular examination of patients with B cell lymphomas is usually normal.

Extremities

CNS

Seizures

References

↑ "StatPearls". 2022. PMID 32644754 Check |pmid= value (help).
↑ "StatPearls". 2022. PMID 29763144.
↑ Hingorjo MR, Syed S (2008). "Presentation, staging and diagnosis of lymphoma: a clinical perspective". J Ayub Med Coll Abbottabad. 20 (4): 100–3. PMID 19999217.
↑ Armitage JO, Gascoyne RD, Lunning MA, Cavalli F (2017). "Non-Hodgkin lymphoma". Lancet. 390 (10091): 298–310. doi:10.1016/S0140-6736(16)32407-2. PMID 28153383.
↑ Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH; et al. (2020). "Hodgkin lymphoma". Nat Rev Dis Primers. 6 (1): 61. doi:10.1038/s41572-020-0189-6. PMID 32703953 Check |pmid= value (help).

Template:WikiDoc Sources

[pmid32644754-1] "StatPearls". 2022. PMID 32644754 Check |pmid= value (help).

[pmid29763144-2] "StatPearls". 2022. PMID 29763144.

[pmid19999217-3] Hingorjo MR, Syed S (2008). "Presentation, staging and diagnosis of lymphoma: a clinical perspective". J Ayub Med Coll Abbottabad. 20 (4): 100–3. PMID 19999217.

[pmid28153383-4] Armitage JO, Gascoyne RD, Lunning MA, Cavalli F (2017). "Non-Hodgkin lymphoma". Lancet. 390 (10091): 298–310. doi:10.1016/S0140-6736(16)32407-2. PMID 28153383.

[pmid32703953-5] Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH; et al. (2020). "Hodgkin lymphoma". Nat Rev Dis Primers. 6 (1): 61. doi:10.1038/s41572-020-0189-6. PMID 32703953 Check |pmid= value (help).

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