Aplastic anemia laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Patients with aplastic anemia have a hypoplastic bone marrow (<20% cellularity), pancytopenia (transfusion-dependent anemia, thrombocytopenia, and severe neutropenia), a low reticulocyte count, and with normal maturation of all cell lines.
Laboratory Findings
- Full blood count (pancytopenia (anemia, thrombocytopenia, and severe neutropenia)
- Peripheral blood smear (normocytic RBC, decreased or absent reticulocytes)
- Bone marrow biopsy (hypoplastic bone marrow (<20% cellularity), and with normal maturation of all cell lines.
- Renal function
- Electrolytes
- Liver enzymes
- Thyroid function tests
- vitamin B12 and folic acid levels.