Milk-alkali syndrome medical therapy

Milk-alkali syndrome Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Milk-alkali syndrome from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Chest X Ray
Ecocardiography and Ultrasound
CT scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Milk-alkali syndrome medical therapy On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Milk-alkali syndrome medical therapy All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Milk-alkali syndrome medical therapy
CDC on Milk-alkali syndrome medical therapy
Milk-alkali syndrome medical therapy in the news
Blogs on Milk-alkali syndrome medical therapy
Directions to Hospitals Treating Milk-alkali syndrome
Risk calculators and risk factors for Milk-alkali syndrome medical therapy

Overview

Treatment of milk-alkali syndrome is mostly supportive and mainly includes withdrawal of the offending agent, hydration and intravenous volume expansion. However, other treatments such as therapy with calcium supplements (in temporary hypocalcemia) and hemodialysis (in acute or chronic irreversible renal insufficiency) may be required.

Medical Therapy

• Treatment of milk-alkali syndrome is mostly supportive, and with early diagnosis and therapy, renal function may return to normal.

• The main treatment of milk-alkali syndrome includes:
  • Withdrawal of the offending agent.
  • Hydration and intravenous volume expansion.

• The above treatments usually resolve the symptoms and abnormalities in milk-alkali syndrome (hypercalcemia, alkalosis and renal insufficiency).

• Additional treatments that may be required include:
  • Calcium supplements may be needed since during therapy temporary hypocalcemia may occur.
  • In hypercalcemic crisis, treatment with intravenous furosemide, pamindronate, and hydrocortisone have been reported to decrease calcium.

Renal replacement with dialysis

Acute or chronic irreversible renal insufficiency may require renal replacement with dialysis.