Lymphangitis causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vendhan Ramanujam M.B.B.S [2]

Overview

Lymphangitis is an inflammation of the lymphatic channels following infectious causes like bacteria, viruses, fungi and parasites with streptococcus pyogenes being the most common cause. It can also occur in the setting of noninfectious causes like congenital or development abnormalities, surgical procedures, malignancy, radiation, and trauma.

Causes

Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. Lymphangitis most often is a sign of a worsening skin infection and may suggest the spreading of the causative organism into the blood, thus it must be treated as such irrespective of the causes.

Common Causes

Group A beta-hemolytic streptococci^[1]

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	No underlying causes
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	Crohn's disease
Genetic	No underlying causes
Hematologic	No underlying causes
Iatrogenic	Radiation
Infectious Disease	Aeromonas hydrophila, bacillus anthracis, blastomycosis, botryomycosis, brugia malayi, brugia timori, brugia, burkholderia pseudomallei, coccidioidomycosis, ehrlichia chaffeensis, ehrlichiosis, erysipelothrix rhusiopathiae, erysipelothrix, filariasis, francisella tularensis, fusobacterium nucleatum, group A beta-hemolytic streptococci, herpes simplex virus, histoplasmosis, leishmania braziliensis, leishmania guyanensis, leishmania major, leishmania mexicana, leishmania panamensis, leishmania tropica, leishmania, leishmaniasis, mycobacterium chelonae, mycobacterium kansasii, mycobacterium marinum, mycobacterium tuberculosis, nocardia, nocardia asteroides, nocardia brasiliensis, pasteurella multocida, peptostreptococcus, prevotella, pseudomonas, rat-bite fever, rhodococcus equi, rickettsia africae, rickettsia sibirica mongolotimonae, spirillum minus, sporothrix schenckii, sporotrichosis, staphylococcus aureus, streptococcus pneumoniae, streptococcus pyogenes, systemic mycoses, tularemia, wuchereria bancrofti
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	No underlying causes
Oncologic	Breast cancer, lung cancer, lymphoma, pancreas cancer, prostate cancer, stomach cancer
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	Contact dermatitis, tuberculin
Sexual	Sclerosing lymphangitis
Trauma	Sclerosing lymphangitis
Urologic	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

References

↑ "Education and imaging. Gastrointestinal: Symmetric lymphangitis of lower limbs originating from a perianal abscess". J Gastroenterol Hepatol. 28 (11): 1690. 2013. PMID 24308045.
↑ Van Kruiningen HJ, Colombel JF (2008). "The forgotten role of lymphangitis in Crohn's disease". Gut. 57 (1): 1–4. doi:10.1136/gut.2007.123166. PMID 18094195.
↑ Sands M, Brown R (1988). "Herpes simplex lymphangitis. Two cases and a review of the literature". Arch Intern Med. 148 (9): 2066–7. PMID 3046547.
↑ Wu JW, Chiles C (1999). "Lymphangitic carcinomatosis from prostate carcinoma". J Comput Assist Tomogr. 23 (5): 761–3. PMID 10524863.
↑ ^5.0 ^5.1 de Sousa R, Duque L, Anes M, Poças J, Torgal J, Bacellar F; et al. (2008). "Lymphangitis in a Portuguese patient infected with Rickettsia sibirica". Emerg Infect Dis. 14 (3): 529–30. doi:10.3201/eid1403.070680. PMC 2570837. PMID 18325289.
↑ Morrison JB (1984). "Lymphangitis after tuberculin tests". Br Med J (Clin Res Ed). 289 (6442): 413. PMC 1442414. PMID 6432121.CS1 maint: PMC format (link)
↑ Akogun OB, Akogun MK, Apake E, Kale OO (2011). "Rapid community identification, pain and distress associated with lymphoedema and adenolymphangitis due to lymphatic filariasis in resource-limited communities of North-eastern Nigeria". Acta Trop. 120 Suppl 1: S62–8. doi:10.1016/j.actatropica.2011.03.008. PMID 21470556.

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[pmid24308045-1] "Education and imaging. Gastrointestinal: Symmetric lymphangitis of lower limbs originating from a perianal abscess". J Gastroenterol Hepatol. 28 (11): 1690. 2013. PMID 24308045.

[pmid18094195-2] Van Kruiningen HJ, Colombel JF (2008). "The forgotten role of lymphangitis in Crohn's disease". Gut. 57 (1): 1–4. doi:10.1136/gut.2007.123166. PMID 18094195.

[pmid3046547-3] Sands M, Brown R (1988). "Herpes simplex lymphangitis. Two cases and a review of the literature". Arch Intern Med. 148 (9): 2066–7. PMID 3046547.

[pmid10524863-4] Wu JW, Chiles C (1999). "Lymphangitic carcinomatosis from prostate carcinoma". J Comput Assist Tomogr. 23 (5): 761–3. PMID 10524863.

[pmid18325289-5] 5.0 ^5.1 de Sousa R, Duque L, Anes M, Poças J, Torgal J, Bacellar F; et al. (2008). "Lymphangitis in a Portuguese patient infected with Rickettsia sibirica". Emerg Infect Dis. 14 (3): 529–30. doi:10.3201/eid1403.070680. PMC 2570837. PMID 18325289.

[pmid6432121-6] Morrison JB (1984). "Lymphangitis after tuberculin tests". Br Med J (Clin Res Ed). 289 (6442): 413. PMC 1442414. PMID 6432121.CS1 maint: PMC format (link)

[pmid21470556-7] Akogun OB, Akogun MK, Apake E, Kale OO (2011). "Rapid community identification, pain and distress associated with lymphoedema and adenolymphangitis due to lymphatic filariasis in resource-limited communities of North-eastern Nigeria". Acta Trop. 120 Suppl 1: S62–8. doi:10.1016/j.actatropica.2011.03.008. PMID 21470556.

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