Small cell carcinoma of the lung medical therapy
Small Cell Carcinoma of the Lung Microchapters |
Differentiating Small Cell Carcinoma of the Lung from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Patients with small cell carcinoma (SCC) of the lung have many treatment options. The selection depends on the stage of the tumor. The options are radiation therapy, chemotherapy, surgery, or a combination of these methods. Before treatment starts, ask your health care team about possible side effects and how treatment may change your normal activities. Because cancer treatments often damage healthy cells and tissues, side effects are common. Side effects may not be the same for each person, and they may change from one treatment session to the next.
Initial Medical Therapy
Limited Stage SCC
Limited stage SCC | |||||||||||||||||||||||||||||||||||||||||||||||||||
Clinical stage T(1-2),N(0) | Limited stage in excess of T(1-2),N(0) | ||||||||||||||||||||||||||||||||||||||||||||||||||
What is the statuses of the pathologic mediastinal staging AND operability of the patient? | What is the performance status of the patient? | ||||||||||||||||||||||||||||||||||||||||||||||||||
Negative pathologic mediastinal staging AND Patient is medically operable | Positive pathologic mediastinal staging OR Patient is medically operable | Good (PS 0-2) | Poor (PS 3-4) due to SCC | Poor (PS 3-4) not due to SCC | |||||||||||||||||||||||||||||||||||||||||||||||
Lobectomy PLUS Lymph node dissection or sampling | Chemotherapy PLUS Thoracic radiation therapy | Chemotherapy WITH/WITHOUT Thoracic radiation therapy | Individualized treatment PLUS supportive care | ||||||||||||||||||||||||||||||||||||||||||||||||
What is the status of involvement of the lymph nodes? | What is the performance status of the patient? | ||||||||||||||||||||||||||||||||||||||||||||||||||
N0 | N+ | Good (PS 0-2) | Poor (PS 3-4) due to SCC | Poor (PS 3-4) not due to SCC | |||||||||||||||||||||||||||||||||||||||||||||||
Chemotherapy | Chemotherapt PLUS Mediastinal radiotherapy | Chemotherapy PLUS Thoracic radiation therapy | Chemotherapy WITH/WITHOUT Thoracic radiation therapy | Individualized treatment PLUS supportive care | |||||||||||||||||||||||||||||||||||||||||||||||