Liposarcoma surgery
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Overview
Surgery
Surgery is the key treatment for liposarcoma that has not metastasized into other organs. Tumor along with a wide margin of healthy tissue is removed to ensure that only healthy tissue is retained. Stage 1 of lims, trunk, head and neck are treated with surgery. Stage 2 and 3 may require radiation and chemotherapy along with surgery for treatment. Following is a classification for surgical resection. [1]
Surgical resection | Proceedure |
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Intraleisional | Curettage, Partial tumor removal |
Marginal | May leave microscopic tumor behind |
Wide | Remove tumor and surrounding cuff of tissue |
Radical | Remove entire compartment including amputation |
Treatment by stage
Treatment by stage involves some basic criteria.[2]. Some of them are given below.
Treatment of stage 1 sarcoma
- Primary treatment is surgery. If the margins are cut >1 cm sparing the fascia, Care after surgery adjuvant treatment. Care includes the following.
- Rehabilitation if needed
- Medical history and physical examination every 3-6 months for every 2-3 years.
- Chest Imaging every 6-12 months
- Tumor site imaging right after surgery and then at regular intervals of time.
- If the margins are cut <1 cm with the fascia, for stage 1A consider radiation therapy and Care after treatment and for stage 1B radiation treatment.
Treatment of stage 2 and stage 3 sarcoma
- For stage 2A , radiation is given as neoadjuvant therapy followed by surgery as a primary treatment and then radiation boost as an adjuavant therapy
- For stage 2B or 3, radiation/ chemotherapy/ chemoradiation are given as neoadjuvant therapy followed by surgery as a primary treatment and radiation boost or chemotherapy as an adjuvant therapy
- For tumors which cannot be surgically resected, radiaion therapy/chemoradiation/ chemotherapy/ isolated limb chemotherapy is given as primary treatment.
- It is followed by surgery if possible and radiation boost/ chemotherapy as a follow up treatment option.
- If surgery is still not feasible, observation if no symptoms/ radiation / palliative chemotherapy or surgery/ amputation / supportive care are the treatment options
Treatment of stage 4 sarcoma
For confined cancer spread |
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Surgery to remove metastasis with chemotherapy and radiation before and after surgery |
Ablation |
Observation |
Stereotactic Body Radiation Therapy (SBRT) |
Embolization |
References
- ↑ Enneking WF, Spanier SS, Goodman MA (1980). "A system for the surgical staging of musculoskeletal sarcoma". Clin Orthop Relat Res (153): 106–20. PMID [ 7449206 [ Check
|pmid=
value (help). - ↑ "NCCN".