Endometrial hyperplasia natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
The majority of cases of endometrial hyperplasia, except complex atypical hyperplasia resolve spontaneously with time.[1] If left untreated, 30% of patients with atypical hyperplasia may progress to develop endometrial carcinoma.[2] Malignant transformation into endometrial cancer is the most common complication of endometrial hyperpasia.[3] Prognosis is generally good with treatment.
Natural History
- The majority of cases of endometrial hypeplasia, except complex atypical hyperplasia resolve spontaneously with time.[1]
- If left untreated, 30% of patients with atypical hyperplasia may progress to develop endometrial carcinoma.[2]
Complications
Malignant transformation is the most common complication of endometrial hyperpasia.[3]
Prognosis
Prognosis is generally good with treatment.
References
- ↑ 1.0 1.1 Terakawa N, Kigawa J, Taketani Y, Yoshikawa H, Yajima A, Noda K; et al. (1997). "The behavior of endometrial hyperplasia: a prospective study. Endometrial Hyperplasia Study Group". J Obstet Gynaecol Res. 23 (3): 223–30. PMID 9255033.
- ↑ 2.0 2.1 Lacey JV, Chia VM (2009). "Endometrial hyperplasia and the risk of progression to carcinoma". Maturitas. 63 (1): 39–44. doi:10.1016/j.maturitas.2009.02.005. PMID 19285814.
- ↑ 3.0 3.1 Endometrial hyperplasia. Radiopedia. http://radiopaedia.org/articles/endometrial-hyperplasia-1 Accessed on March 16, 2016