Hemophilia A classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Fahd Yunus, M.D. [2]

Overview

Hemophilia A may be classified according to the amount of Factor VIII present, resulting in either a mild, moderate, or severe form of the disease.

Classification

• Mild hemophilia – 5-40% of normal factor VIII activity in the blood
• Moderate hemophilia – 1-5% of normal factor VIII activity in the blood
• Severe hemophilia – less than 1% of normal factor VIII activity in the blood