Postpartum thyroiditis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

The most potent risk factor in the development of PPT is genetic. Other risk factors include smoking, increase or decreased intake of Iodine, hepatitis C, radiations and medications.

Risk Factors

  • The most potent risk factor in the development of PPT is genetic. Other risk factors include smoking, increase or decreased intake of Iodine, hepatitis C, radiations and medications.

Common Risk Factors

  • Common risk factor in the development of PPT is genetic and includes
    • CD60 CTLA-4 gene
    • HLA DR-3, HLA DR4, and HLA DR5 antigens halpotypes.
    • Subsequent pregnancies

Less Common Risk Factors

  • Less common risk factors in the development of PPT are environmental and they include:
    • Smoking
    • Intake of Iodine
    • Radiation
    • Medications: lithium, amiodarone, interferon alpha, interleukin 2, and the highly active anti-retroviral therapy.
    • Systemic lupus erythromatosis
    • Multiple Sclerosis
    • Thyroid hormone resistance syndrome

References

doi: 10.2478/folmed-2014-0021Template:WH Template:WS