Postpartum thyroiditis future or investigational therapies
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Postpartum thyroiditis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sunny Kumar MD [2]
Overview
Postpartum thyroiditis is under research for establishing exact parthenogenesis and treatment.
Future or Investigational Therapies
Postpartum thyroiditis is under research for establishing exact parthenogenesis and treatment. Clinical trails for establishing treatment of Postpartum thyroiditis (PPT) is under way. However anti-TPO high titers have been associated with chances of PPT occurrence but it is not always the case so the mechanism of autoimmune system causing transient destruction of thyroid follicles during postpartum is largely under debate.
Thyroid hormone plays important role in development of fetus and its malfunction leads to significant female morbidity so preventive measure as use of selenium and adequate iodine uptake are under trails to establish significant role on large scale.
Microscopic picture of late phase of PPT are similar to silent thyroiditis however there is limited data on early microscopic picture of PPT which is different than other autoimmune disease of thyroid gland
There is limited amount of literature on novel gene for CD60 CD4 T cell mutation which play role in PPT etiopathogensis and it is under research to gather more case studies.