Monoclonal gammopathy of undetermined significance history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2]
Overview
The majority of patients with Monoclonal gammopathy of undetermined significance are asymptomatic. Patients with MGUS have no symptoms of myeloma or related malignancy that can be attributable to their monoclonal protein. During evaluation for one of a variety of clinical symptoms and disorders that include peripheral neuropathy, vasculitis, hemolytic anemia, skin rashes, hypercalcemia, elevated erythrocyte sedimentation rate etc , It is often an incidental finding on protein electrophoresis.[1].
History and Symptoms
- The patients with Monoclonal gammopathy of undetermined significance are asymptomatic. It's discovery is often incidental, found during evaluation of other clinical symptoms.[1]
References
- ↑ 1.0 1.1 Therneau TM, Kyle RA, Melton LJ, Larson DR, Benson JT, Colby CL, Dispenzieri A, Kumar S, Katzmann JA, Cerhan JR, Rajkumar SV (November 2012). "Incidence of monoclonal gammopathy of undetermined significance and estimation of duration before first clinical recognition". Mayo Clin. Proc. 87 (11): 1071–9. doi:10.1016/j.mayocp.2012.06.014. PMC 3541934. PMID 22883742.