Endometrial hyperplasia screening

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Badria Munir M.B.B.S.[2] , Soujanya Thummathati, MBBS [3]

Oveview

Routine screening for endometrial hyperplasia or endometrial carcinoma is not recommended.

Screening

  • Women receiving unopposed estrogens need endometrial sampling once every 2 years (relative risk increases only after 2 years of estrogen use), particularly if endometrial hyperstimulation has been documented previously and has not been treated by short-term administration of progestins. [1]
  • Also, if the informed, high-risk individual requests an endometrial evaluation before or during HRT or at any time during her periodic health examinations, she should not be deprived of an office-based investigative procedure to rule out endometrial pathology.
  • An endometrial evaluation also should be performed in women at high risk for endometrial carcinoma, such as women with history of Lynch II syndrome.

References

  1. Hakala T, Mecklin JP, Forss M, Järvinen H, Lehtovirta P (October 1991). "Endometrial carcinoma in the cancer family syndrome". Cancer. 68 (7): 1656–9. PMID 1893367.

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