Haff disease electrocardiogram

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S

Overview

Haff disease may result in cardiac arrhythmias due to hyperkalemia and hypocalcemia, as a result of rhabdomyolysis. Therefore, it is essential to monitor the patient with an ECG.

Electrocardiogram

Since Haff disease causes rhabdomyolysis, it is essential to monitor the patient for cardiac arrhythmias due to hyperkalemia or hypocalcemia.[1]

ECG features of hyperkalemia include:[2]

  • Small or absent P wave
  • Prolonged PR interval
  • Augmented R wave
  • Wide QRS complex
  • Peaked T waves
ECG changes seen in hyperkalemia


ECG features of hypocalcemia include:[3]

  • Prolonged QTc interval (risk factor for Torsades de pointes)
ECG changes seen in hypocalcemia

References

  1. Keltz E, Khan FY, Mann G (2013). "Rhabdomyolysis. The role of diagnostic and prognostic factors". Muscles Ligaments Tendons J. 3 (4): 303–12. PMC 3940504. PMID 24596694.
  2. "StatPearls". 2022. PMID 29261936.
  3. "StatPearls". 2022. PMID 28613662.

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