Human respiratory syncytial virus causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Template:BA
Overview
Influenza infection is caused by the influenza virus that belong to the family Orthomyxoviridae. Three types of influenza virus have been reported to cause clinical illness in humans: types A, B, and C. Influenza virus can be found in humans, as well as in poultry, pigs, and bats.
Taxonomy
- The scientific name of the virus is respiratory syncytial virus (hRSV)
- Other names include human orthopneumovirus or respiratory syncytial virus (RSV).
- Member of the Pneumoviridae family and Orthopneumovirus genus.
- Enveloped, negative sense, single stranded RNA virus[1].
- Main subtypes are A and B. Most evidence suggests no difference in disease severity between both subtypes[2].
- RSV fusion protein facilitates the fusion of the viral envelope with the host cell membrane. This protein is a target for vaccines and anti-viral agents.
- Transmission:
* There are no animal reservoirs for this virus. * Spread via nasal or oral secretions, either directly via large droplets (and probably aerosolized particles) or indirectly through contact with contaminated hands and environmental surfaces (e.g. cribs, toys, doorknobs, tabletops)
Mnemonic name HRSV Taxon ID: 11250 Scientific name: Human respiratory syncytial virus Parent Orthopneumovirus Children Human respiratory syncytial virus A Human respiratory syncytial virus B unclassified Human respiratory syncytial virus Other names Human orthopneumovirus human RSV Rank species Lineage Viruses > Riboviria > Orthornavirae > Negarnaviricota > Haploviricotina > Monjiviricetes > Mononegavirales (negative-sense genome single-stranded RNA viruses) > Pneumoviridae > Orthopneumovirus Hosts Human Links www.ncbi.nlm.nih.gov
References
- ↑ Rey-Jurado E, Kalergis AM (2017). "Immunological Features of Respiratory Syncytial Virus-Caused Pneumonia-Implications for Vaccine Design". Int J Mol Sci. 18 (3). doi:10.3390/ijms18030556. PMC 5372572. PMID 28273842.
- ↑ Devincenzo JP (2004). "Natural infection of infants with respiratory syncytial virus subgroups A and B: a study of frequency, disease severity, and viral load". Pediatr Res. 56 (6): 914–7. doi:10.1203/01.PDR.0000145255.86117.6A. PMID 15470202.