Focal segmental glomerulosclerosis medical therapy

Focal segmental glomerulosclerosis Microchapters
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Differentiating Focal segmental glomerulosclerosis from other Diseases
Epidemiology and Demographics
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Diagnostic Study of Choice
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief:’’’ Cafer Zorkun, M.D., Ph.D. [2]

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Medical Therapy

• Salt restriction and diuretics (water pills), such as furosemide, for edema
• Antihypertensives (especially ACEIs) - if the blood pressure is too high
• treat present hyperlipidemia (e.g. statins, fibrates)
• Corticosteroids, such as prednisone - based on the clinical judgment of physician (no broad consensus/guideline)
• Cytotoxics, such as cyclophosphamide may be used to induce remission in patients presenting with FSGS refractory to corticosteroids, or in patients who do not tolerate steroids.
• Plasmapheresis - blood cleansing using a machine to remove the patient's blood plasma and replacing it with donor plasma.
• None - sometimes none of the above works and the patient will required dialysis with possibly later transplantation of a new kidney.