Small cell carcinoma of the lung medical therapy
|
Small Cell Carcinoma of the Lung Microchapters |
|
Differentiating Small Cell Carcinoma of the Lung from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Small cell carcinoma of the lung medical therapy On the Web |
|
American Roentgen Ray Society Images of Small cell carcinoma of the lung medical therapy |
|
Small cell carcinoma of the lung medical therapy in the news |
|
Directions to Hospitals Treating Small cell carcinoma of the lung |
|
Risk calculators and risk factors for Small cell carcinoma of the lung medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Patients with small cell carcinoma (SCC) of the lung have many treatment options. The selection depends on the stage of the tumor. The options are radiation therapy, chemotherapy, surgery, or a combination of these methods. Before treatment starts, ask your health care team about possible side effects and how treatment may change your normal activities. Because cancer treatments often damage healthy cells and tissues, side effects are common. Side effects may not be the same for each person, and they may change from one treatment session to the next.
Initial Medical Therapy
Limited Stage SCC
| Limited stage SCC | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Clinical stage T(1-2),N(0) | Limited stage in excess of T(1-2),N(0) | ||||||||||||||||||||||||||||||||||||||||||||||||||
| What is the statuses of the pathologic mediastinal staging AND operability of the patient? | What is the performance status of the patient? | ||||||||||||||||||||||||||||||||||||||||||||||||||
| Negative pathologic mediastinal staging AND Patient is medically operable | Positive pathologic mediastinal staging OR Patient is medically operable | Good (PS 0-2) | Poor (PS 3-4) due to SCC | Poor (PS 3-4) not due to SCC | |||||||||||||||||||||||||||||||||||||||||||||||
| Lobectomy PLUS Lymph node dissection or sampling | What is the performance status of the patient? | Chemotherapy PLUS Thoracic radiation therapy | Chemotherapy WITH/WITHOUT Thoracic radiation therapy | Individualized treatment PLUS supportive care | |||||||||||||||||||||||||||||||||||||||||||||||
| What is the status of involvement of the lymph nodes? | Good (PS 0-2) | Poor (PS 3-4) due to SCC | Poor (PS 3-4) not due to SCC | ||||||||||||||||||||||||||||||||||||||||||||||||
| N0 | N+ | Chemotherapy PLUS Thoracic radiation therapy | Chemotherapy WITH/WITHOUT Thoracic radiation therapy | Individualized treatment PLUS supportive care | |||||||||||||||||||||||||||||||||||||||||||||||
| Chemotherapy | Chemotherapy PLUS Mediastinal radiotherapy | ||||||||||||||||||||||||||||||||||||||||||||||||||
Extensive Stage
| Extensive stage | |||||||||||||||||||||||||||||||||||||||||||||||
| Is there symptomatic localized metastasis OR metastasis to the brains? | |||||||||||||||||||||||||||||||||||||||||||||||
| No | Yes, there is symptomatic localized metastasis | Yes, there is brain metastasis | |||||||||||||||||||||||||||||||||||||||||||||
| What is the performance status of the patient? | What metastasis related symptoms does the patient have? | Is the patient symptomatic? | |||||||||||||||||||||||||||||||||||||||||||||
| Good (PS 0-2) OR Poor (3-4) due to SCLC | Poor (3-4) not due to SCLC | Superior vena cava syndrome OR Lobar obstruction OR Bone metastasis | Spinal cord compression | Yes | No | ||||||||||||||||||||||||||||||||||||||||||
| Combination chemotherapy PLUS Supportive care | Individualized therapy PLUS Supportive care | Chemotherapy PLUS Radiation therapy to the sites of metastasis | Radiation therapy to the sites of metastasis THEN Chemotherapy (unless medical therapy is immediately necessary) | Whole brain radiation therapy THEN Chemotherapy (unless medical therapy is immediately necessary) | Chemotherapy PLUS Whole brain radiation therapy | ||||||||||||||||||||||||||||||||||||||||||