Liposarcoma laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overview

Laboratory Findings

Biopsy

Although imaging assists in the diagnosis of liposarcoma, a biopsy is needed to confirm the disease and determine the histopathological subtype of liposarcoma.


Subtype	Findings

Atypical Lipomatous Neoplasm (ALN)/Well-Differentiated Liposarcoma (WDL)	Multivacuolated adipose cells and spindle cells with a hyperchromatic nuclei. Fibrotic areas and atypical stroma cells.
Dedifferentiated Liposarcoma
Myxoid Liposarcoma
Pleomorphic Liposarcoma

Table adapted from ^[1]

Well Differentiated Liposarcoma. Image courtesy of Wikimedia Commons.	Dedifferentiated Liposarcoma. Image courtesy of Wikimedia Commons.	Dedifferentiated Liposarcoma. Image courtesy of Wikimedia Commons.
Dedifferentiated Liposarcoma. Image courtesy of Wikimedia Commons.	Dedifferentiated Liposarcoma. Image courtesy of Wikimedia Commons.