Liposarcoma staging

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overview

The staging for liposarcoma is based on the TNM classification, depending on the primary tumor, lymph node involvement, metastasis and the histological grade of the tumor.

Staging

Primary Tumor (T) Tx Tumor cannot be assessed. T0 No evidence of primary tumor. T1 Tumor ≤ 5 cm T1a Superficial tumor (not invading the fascia) T1b Deep tumor T2 Tumor > 5 cm T2a Superficial tumor (not invading the fascia) T2b Deep tumor Table adapted from National Cancer Institute

Lymph Nodes (N) NX Lymph nodes cannot be assessed. N0 No regional lymph node involvement. N1 Regional lymph node involvement. Table adapted from National Cancer Institute Metastasis (M) M0 No distant metastasis M1 Distant metastasis Table adapted from National Cancer Institute

Stages	Primary Tumor (T)	Lymph Node (N)	Metastasis (M)	Histopathological Grading
Stage IA	T1a, T1b	N0	M0	Low grade
Stage IB	T2a, T2b	N0	M0	Low grade
Stage IIA	T1a, T1b	N0	M0	High grade
Stage IIB	T2a, T2b	N0	M0	High grade
Stage III	Any T	N0, N1	M0	High grade
Stage IV	Any T	Any N	M1	Any grade
Table adapted from National Cancer Institute