Fever of unknown origin laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: febris continua e causa ignota; febris e causa ignota; febris E.C.I.; fever/pyrexia of obscured/undetermined/uncertain/unidentifiable/unknown focus/origin/source; fever/pyrexia without a focus/origin/source; FUO; PUO
Overview
Laboratory Workup of Fever of Unknown Origin
- Complete blood count with differential
- Basic metabolic panel
- Liver function test including AST, ALT, LDH, bilirubin, and alkaline phosphatase
- Creatine kinase
- Blood cultures (at least 2 sets)
- Urinalysis with microscopic examination
- Urine cultures
- Erythrocyte sedimentation rate
- C-reactive protein
- Gamma-glutamyl transferase
- Coombs test
- Cold agglutinins
- Ferritin
- Angiotensin-converting enzyme
- Thyroid peroxidase and anti-thyroglobulin antibodies
- Antinuclear antibodies
- Rheumatoid factor
- Cryoglobulins
- Cytomegalovirus serology and heterophile antibody test if positive for atypical lymphocytes
- Q fever serology for patients with exposure to livestocks
- HIV serology
- Serum protein electrophoresis
- Tuberculin skin test
- Fecal occult blood test[1][2]
References
- ↑ Hirschmann, J. V. (1997-03). "Fever of unknown origin in adults". Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America. 24 (3): 291–300, quiz 301-302. ISSN 1058-4838. PMID 9114175. Check date values in:
|date=(help) - ↑ Cunha, Burke A. (2007-12). "Fever of unknown origin: focused diagnostic approach based on clinical clues from the history, physical examination, and laboratory tests". Infectious Disease Clinics of North America. 21 (4): 1137–1187, xi. doi:10.1016/j.idc.2007.09.004. ISSN 0891-5520. PMID 18061092. Check date values in:
|date=(help)