Liposarcoma history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
Liposarcoma usually presents as a painless mass. The most common location of a liposarcoma is the lower extremities. Patients with retroperitoneal liposarcoma remain asymptomatic until the mass invades adjacent structures, which may cause pain or obstructive symptoms.
History and symptoms
- Symptoms of liposarcoma will depend on the location of the tumor.
- Liposarcomas located in the deep soft tissue of the extremities presents as a painless mass that grows slowly over several months.
- Superficial liposarcomas are commonly located in the lower extremities, especially in the femoral and popliteal regions.
Retroperitoneal liposarcoma
- The majority of patients with retroperitoneal liposarcoma remain asymptomatic until the tumor grows to a considerable size (10-20 cm).
- Common symptoms of retroperitoneal liposarcoma include weight loss and abdominal pain.[1]
- The tumor may compress adjacent organs and vascular structures to cause pain or obstructive symptoms.[2]
- The kidneys or ureters may also be involved, which may result in urologic symptoms, such as oliguria, or renal failure.
Esophageal liposarcoma
- Esophageal liposarcoma is extremely rare.[3]
- Esophageal liposarcomas may cause dysphagia, vomiting, cough, gastrointestinal bleeding, and hoarseness.[3]
Bowel Liposarcoma
- Symptoms of gastrointestinal bleeding are common manifestations of liposarcoma located in the small bowel and the colon.[4]
Mediastinal Liposarcoma
- Mediastinal liposarcomas are rare
- Symptoms include dyspnea, cough, chest pain, and weight loss.[5]
References
- ↑ Grasso, Emanuele; Marino, Fabio; Bottalico, Michele; Simone, Michele (2014). "A Case of Myxoid Liposarcoma of the Retroperitoneum: A Challenging Tumour for Diagnosis and Treatment". Case Reports in Surgery. 2014: 1–4. doi:10.1155/2014/572805. ISSN 2090-6900.
- ↑ McGrath, Patrick C. (1994). "Retroperitoneal sarcomas". Seminars in Surgical Oncology. 10 (5): 364–368. doi:10.1002/ssu.2980100509. ISSN 8756-0437.
- ↑ 3.0 3.1 Dowli, A.; Mattar, A.; Mashimo, H.; Huang, Q.; Cohen, D.; Fisichella, P. M.; Lebenthal, A. (2014). "A Pedunculated Giant Esophageal Liposarcoma: a Case Report and Literature Review". Journal of Gastrointestinal Surgery. doi:10.1007/s11605-014-2628-8. ISSN 1091-255X.
- ↑ Simon Nennstiel, Martin Mollenhauer, Christoph Schlag, Valentin Becker, Bruno Neu, Norbert Huser, Ralf Gertler, Roland M. Schmid & Stefan von Delius (2014). "Small bowel pleomorphic liposarcoma: a rare cause of gastrointestinal bleeding". Case reports in gastrointestinal medicine. 2014: 391871. doi:10.1155/2014/391871. PMID 25161780.
- ↑ Fukuhara, Shinichi; Dimitrova, Kamellia R; Geller, Charles M; Hoffman, Darryl M; Ko, Wilson; Tranbaugh, Robert F (2014). "Progressive dyspnea in patient with large mediastinal mass". Journal of Cardiothoracic Surgery. 9 (1): 6. doi:10.1186/1749-8090-9-6. ISSN 1749-8090.