Familial adenomatous polyposis surgery
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Familial adenomatous polyposis Microchapters |
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Differentiating Familial adenomatous polyposis from other Diseases |
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Familial adenomatous polyposis surgery On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Surgery is the mainstay of treatment for familial adenomatous polyposis.
Surgery
- Treatment for FAP depends on the genotype. Most individuals with the APC mutation will develop colon cancer by the age of 40.
- Prophylatic surgery is generally recommended before the age of 25.
- There are several surgical options that involve the removal of either the colon or both the colon and rectum.
- The decision to remove the rectum depends on the number of polyps in the rectum as well as the family history.
- If the rectum has few polyps, the colon is removed and the small bowel (ileum) is connected to the rectum (ileorectal anastomosis).
- If the rectum is involved then the colon and rectum are removed and the patient may require an ileostomy or have an ileoanal pouch reconstruction.