Small intestine cancer natural history, complications, and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Depending on the extent of the tumor at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor. Small intestine adenocarcinoma is associated with a 5 year survival rate of 20%.

Prognosis

The overall 5-year survival rate for resectable adenocarcinoma is only 20%. The 5-year survival rate for resectable leiomyosarcoma, the most common primary sarcoma of the small intestine, is approximately 50%.

The prognosis of small intestine cancer depends on the following:

• Whether or not the tumor can be removed by surgery
• The stage of the cancer, the size of the tumor, whether the cancer has spread outside the small intestine
• The patient’s general health
• Whether the cancer has just been diagnosed or has recurred