Mast cell leukemia natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]

Overview

Prognosis is generally poor, and the median survival time is less than six months.

Prognosis

• Mast cell leukemia is by far an incurable disease with an aggressive behavior.
• Prognosis is generally poor, and the median survival time is less than six months.

Prognostic factors

• Advanced age
• History of weight loss
• Anemia
• Thrombocytopenia
• Hypoalbuminemia
• Excess of bone marrow blasts