Uveitis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]
Overview
There are no established risk factors for most etiologies of uveitis. Some underlying causes have potent risk factors for developing uveitis.
Risk factors
There are no established risk factors for most etiologies of uveitis. Some underlying causes may have potent risk factors for developing uveitis such as:
Acute posterior multifocal placoid pigment epitheliopathy: HLA-B27 or HLA-DR2 alleles, preceding viral illness, underlying vasculitis
CMV retinitis: HIV, CD4 count <50, severe immunosuppression, localized ocular immunosuppression
Necrotizing herpitic retinitis: Immunosuppression
Punctuate inner choroidopathy: Myopia in females, age 18 to 40
Sarcoid uveitis: African American race, age<50
Autoimmune scleritis: Female gender, age 40-60 years
Sympathetic ophthalmia: ocular trauma with delayed closing of the wound
Acute anterior uveitis: HLA-B27 allele, ankylosing spondylitis, psoraitic arthritis
TINU syndrome: Female gender
Vogt-Koyanagi-Harada disease: Hispanic or Japanese race, HLA-DR1 and HLA-DR4 alleles
Drug-induced uveitis: Use of rifabutin, cidofovir, bisphosphonates, sulfonamides, moxifloxacin, metipranolol, brimonidine, prostaglandin analogues, flurbiprofen