Goodpasture syndrome medical therapy
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Goodpasture syndrome Microchapters |
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Diagnosis |
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Treatment |
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Goodpasture syndrome medical therapy On the Web |
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American Roentgen Ray Society Images of Goodpasture syndrome medical therapy |
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Risk calculators and risk factors for Goodpasture syndrome medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The mainstay of therapy for Goodpasture syndrome is corticosteriods, cyclophosphamide and plasmapheresis.
Medical Therapy
Goodpasture’s syndrome responds well to treatment with corticosteroids immunosuppressants, and plasmapheresis. Treatment of Goodpasture's should begin before serum creatinine levels are greater than 5.7mg/dl, before the development of anuria, and the need for renal dialysis. Corticosteriods are given for at least 6 months in tapering doses, immunosuppressants asre given for 2 to 3 months, and plasmapheresis is given for 10 to 14 treatments.
An alternative treatment used for Goodpasture's is rituximab. The use of rituximab for 2 to 4 weeks is beneficial in the recovery of renal function in patients undergoing renal dialysis. However, its use as an induction therapy for Goodpasture's is not ideal because of its slow activation time.