Bourbon virus infection overview
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Historical Perspective
In 2014, Olga Kosoy, from the Centers for Disease Control and Prevention isolated Bourbon virus for the first time from a blood sample of an infected person in Bourbon County, Kansas, United States.
Classification
There is no established classification system for Bourbon virus infection.
Pathophysiology
Causes
Bourbon virus infection is caused by a type of thogotovirus, which belongs to Orthomyxoviridae family. It is a single-stranded, negative-sense RNA virus, which is segmented and exists in two different morphologies.[1]
Differentiating Bourbon virus infection from other Diseases
Epidemiology and Demographics
Risk Factors
The most potent risk factor in the development of Bourbon virus infection is a tick bite. Other risk factors include traveling or residing within endemic regions will increase chances of infection.
Screening
According to CDC, there is insufficient evidence to recommend routine screening for Bourbon virus infection.[2]
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
X ray
CT scan
MRI
Ultrasound
Other Imaging findings
Other Diagnostic Studies
Treatment
Medical Therapy
There is no specific treatment, cure, or vaccine for Bourbon virus infection. Early diagnosis, hospitalization, and supportive therapy are fundamentals of treatment.
Surgery
Primary Prevention
Secondary Prevention
References
- ↑ Lambert AJ, Velez JO, Brault AC, Calvert AE, Bell-Sakyi L, Bosco-Lauth AM, Staples JE, Kosoy OI (2015). "Molecular, serological and in vitro culture-based characterization of Bourbon virus, a newly described human pathogen of the genus Thogotovirus". J. Clin. Virol. 73: 127–32. doi:10.1016/j.jcv.2015.10.021. PMID 26609638.
- ↑ "Bourbon virus | Division of Vector-Borne Diseases (DVBD) | NCEZID | CDC".