Liposarcoma MRI
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
MRI is the optimal imaging test for the diagnosis of liposarcoma. MRI findings for a well-differentiated liposarcoma include a mass with at least 75% of adipose content with thin irregular septa. MRI also evaluates the size, location, and depth of the mass. MRI findings help to differentiate between the different subtypes of liposarcoma and help to assess distant metastasis.
MRI
- MRI findings for a well-differentiated liposarcoma include a mass with at least 75% of adipose content with thin irregular septa. [1]
- Other subtypes may demonstrate fewer adipose content.
- Thick septa inside the mass are associated with a malignant disease and poorer prognosis.
- Hemorrhage and necrosis may be observed within the mass among patients with the de-differentiated subtype of liposarcoma.
- Typically, myxoid liposarcoma has a low signal intensity on T1, in contrast to well-differentiated liposarcoma that has a high intensity signal on T1 due to the presence of high adipose content. [2]
- The myxoid subtype may be associated with a cystic appearance on MRI among approximately 20% of cases. The myxoid subtype may also appear multilobulated. [3]
References
- ↑ Peterson, Jeffrey J.; Kransdorf, Mark J.; Bancroft, Laura W.; O'Connor, Mary I. (2003). "Malignant fatty tumors: classification, clinical course, imaging appearance and treatment". Skeletal Radiology. 32 (9): 493–503. doi:10.1007/s00256-003-0647-8. ISSN 0364-2348.
- ↑ M. S. Sung, H. S. Kang, J. S. Suh, J. H. Lee, J. M. Park, J. Y. Kim & H. G. Lee (2000). "Myxoid liposarcoma: appearance at MR imaging with histologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (4): 1007–1019. doi:10.1148/radiographics.20.4.g00jl021007. PMID 10903690. Unknown parameter
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ignored (help) - ↑ M. S. Sung, H. S. Kang, J. S. Suh, J. H. Lee, J. M. Park, J. Y. Kim & H. G. Lee (2000). "Myxoid liposarcoma: appearance at MR imaging with histologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (4): 1007–1019. doi:10.1148/radiographics.20.4.g00jl021007. PMID 10903690. Unknown parameter
|month=
ignored (help)