VIPoma surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Madhu Sigdel M.B.B.S.[2]Parminder Dhingra, M.D. [3]
Overview
Surgery is the mainstay of treatment for VIPoma. Surgery should be considered after initial symptomatic management of VIPoma in operable cases. Complete surgical resection of tumor is the only curative treatment for VIPoma. If the tumor cannot be removed completely, surgical debulking may have palliative effect for control of hormonal symptoms.
Surgery
- Surgery should be considered after initial symptomatic management of VIPoma in operable cases.
- Complete surgical resection of tumor is the only curative treatment for VIPoma. The feasibility of surgery depends on the stage of VIPoma at diagnosis.[1]
- If the tumor cannot be removed completely, surgical debulking may have palliative effect for control of hormonal symptoms.[2]
- In nonresectable liver metastases, Hepatic TACE (transarterial chemoembolization) is emerging as a new non-emergency therapeutic modality highly successful for control of VIP-related symptoms.[3]
References
- ↑ Pancreatic Neuroendocrine Tumors (Islet Cell Tumors). National Cancer Institute. http://www.cancer.gov/types/pancreatic/hp/pnet-treatment-pdq#section/_78. Accessed on October 21, 2015.
- ↑ Vinik A. Vasoactive Intestinal Peptide Tumor (VIPoma) [Updated 2013 Nov 28]. In: De Groot LJ, Beck-Peccoz P, Chrousos G, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: http://www.ncbi.nlm.nih.gov/books/NBK278960/
- ↑ Blaise A, Girardet JL (1969). "[Study of the magnetic properties of siderophilin]". C R Acad Sci Hebd Seances Acad Sci D. 269 (10): 966–8. PMID 4981295.