Familial adenomatous polyposis natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2], Mohamad Alkateb, MBBCh [3]
Overview
Natural history
Without colectomy, the patient will develop symptoms of colon cancer, which will eventually lead to death.
Complications
Complications that can develop as a result of familial adenomatous polyposis are:[1]
- Colon cancer
- Duodenal and ampullary cancer
- They are major causes of death after polypectomy
- End-viewing duodenoscopy and side-viewing duodenoscopy are conducted for surveillance.
- Melena
- Cachexia
- Anemia
Prognosis
The prognosis of familial adenomatous polyposis is excellent with treatment. Without treatment, familial adenomatous polyposis will result in colon cancer.
References
- ↑ Iaquinto, Gaetano; Fornasarig, Mara; Quaia, Michele; Giardullo, Nicola; D'Onofrio, Vittorio; Iaquinto, Salvatore; Di Bella, Simone; Cannizzaro, Renato (2008). "Capsule endoscopy is useful and safe for small-bowel surveillance in familial adenomatous polyposis". Gastrointestinal Endoscopy. 67 (1): 61–67. doi:10.1016/j.gie.2007.07.048. ISSN 0016-5107.