Familial adenomatous polyposis surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2], Mohamad Alkateb, MBBCh [3]
Overview
Surgery is the mainstay of treatment for familial adenomatous polyposis. The preferred surgery technique is laparoscopic total proctocolectomy with ileal pouch anal anastomosis (IPAA) and mucosectomy.
Indications
- Surgery is recommended in patients with:[1][2]
- Diffuse polyposis
- High-grade dysplasia on colonoscopy
- Invasive adenocarcinoma on colonoscopy
Surgery
- Surgery is the mainstay of treatment for familial adenomatous polyposis.
- The preferred surgical technique is:
- Laparoscopic total proctocolectomy with ileal pouch anal anastomosis (IPAA) and mucosectomy which has:[1]
- Good patient satisfaction
- Excellent functional outcome
- Few postoperative complications
- No colorectal occurrence or recurrence
- Laparoscopic total proctocolectomy with ileal pouch anal anastomosis (IPAA) and mucosectomy which has:[1]
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- Other surgical techniques include:
- Total colectomy with ileorectal anastomosis
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References
- ↑ 1.0 1.1 Kennedy, Raelene D.; Potter, D. Dean; Moir, Christopher R.; El-Youssef, Mounif (2014). "The natural history of familial adenomatous polyposis syndrome: A 24year review of a single center experience in screening, diagnosis, and outcomes". Journal of Pediatric Surgery. 49 (1): 82–86. doi:10.1016/j.jpedsurg.2013.09.033. ISSN 0022-3468.
- ↑ King JE, Dozois RR, Lindor NM, Ahlquist DA (2000). "Care of patients and their families with familial adenomatous polyposis". Mayo Clin. Proc. 75 (1): 57–67. doi:10.4065/75.1.57. PMID 10630758.